Faculty Collaboration Database

Depressive Symptom Frequency and Prevalence of Cardiovascular Diseases-Analysis of Patients in the National Health and Nutrition Examination Survey. Am J Ther 2015;22(5):382-7

Date

02/07/2015

Pubmed ID

25658955

DOI

10.1097/MJT.0000000000000043

Scopus ID

2-s2.0-84941874955 (requires institutional sign-in at Scopus site)   8 Citations

Abstract

Although depression has been reported to be associated with various cardiovascular risk factors, whether an association exists between depression and prevalence of cardiovascular events is not well known. In particular, the effect of symptom frequency and cardiovascular events has not been described. Data were collected for patients older than 45 years from the 2007-2008 National Health and Nutrition Examination Survey (NHANES) data to study whether an association exists between depression and prevalence of coronary artery disease (CAD), myocardial infarction (MI), congestive heart failure (CHF), and stroke. The NHANES database is a nationally representative probability sample of noninstitutionalized US civilians. We divided patients feeling down/depressed/hopeless into 1 of the 2 categories: symptoms less than half the days of the week and those with less frequent symptoms. Logistic regression analysis was used to adjust for other covariates. A P value of <0.05 was considered statistically significant. More than 2700 patients were studied to analyze the association between severity of depression and prevalence of CAD, MI, CHF, and stroke. Significant associations were noted between depressive symptoms and prevalence of CAD, MI, CHF, and stroke. Those who reported being depressed more than half of the days of the week had 1.95 times greater odds of CAD [95% confidence interval (CI), 1.2473-3.0523], 2.54 times greater odds of CHF (95% CI, 1.6114-4.0126), 2.65 times greater odds of MI (95% CI, 1.7789-3.9521), and 1.91 greater odds of stroke (95% CI, 1.2002-3.0356) when compared with those who reported being depressed less than half of the days of the week. The results of this study suggest that the prevalence of CAD, MI, CHF, and stroke are significantly increased in individuals who report feeling down/depressed/hopeless for more than half the days of the week.

Author List

Loomba RS, Aggarwal S, Arora R

MESH terms used to index this publication - Major topics in bold

Aged
Body Mass Index
Cardiovascular Diseases
Coronary Artery Disease
Depression
Female
Heart Failure
Humans
Logistic Models
Male
Middle Aged
Myocardial Infarction
Nutrition Surveys
Prevalence
Risk Factors
Severity of Illness Index
Smoking
Stroke