Faculty Collaboration Database

Consensus statement for brachytherapy for the treatment of medically inoperable endometrial cancer. Brachytherapy 2015;14(5):587-99

Date

07/19/2015

Pubmed ID

26186975

DOI

10.1016/j.brachy.2015.06.002

Scopus ID

2-s2.0-84940028442 (requires institutional sign-in at Scopus site)   97 Citations

Abstract

PURPOSE: The purpose of this consensus statement from the American Brachytherapy Society (ABS) is to summarize recent advances and to generate general guidelines for the management of medically inoperable endometrial cancer patients with radiation therapy.

METHODS: Recent advances in the literature were summarized and reviewed by a panel of experts. Panel members participated in a series of conference calls and were surveyed to determine their current practices and patterns. This document was reviewed and approved by the full panel, the ABS Board of Directors and the ACR Commission on Radiation Oncology.

RESULTS: A transition from two-dimensional (2D) to three-dimensional (3D) treatment planning for the definitive treatment of medically inoperable endometrial cancer is described. Magnetic resonance (MR) imaging can be used to define the gross tumor volume (GTV), clinical target volume (CTV), and the organs at risk (OARs). Brachytherapy alone can be used for medically inoperable endometrial cancer patients with clinical Stage I cancer with no lymph node involvement and no evidence of deep invasion of the myometrium on MR imaging. In the absence of MR imaging, a combined approach using external beam and brachytherapy may be considered.

CONCLUSIONS: Recent advances support the use of MR imaging and 3D planning for brachytherapy treatment for medically inoperable endometrial cancer.

Author List

Schwarz JK, Beriwal S, Esthappan J, Erickson B, Feltmate C, Fyles A, Gaffney D, Jones E, Klopp A, Small W Jr, Thomadsen B, Yashar C, Viswanathan A

Author

Beth A. Erickson MD Professor in the Radiation Oncology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Brachytherapy
Carcinoma
Consensus
Endometrial Neoplasms
Female
Humans
Magnetic Resonance Imaging
Neoplasm Staging
Organs at Risk
Radiography
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted