Faculty Collaboration Database

Planned Descemetorhexis Without Endothelial Keratoplasty in Eyes With Fuchs Corneal Endothelial Dystrophy. Cornea 2015 Sep;34(9):1149-51

Date

07/18/2015

Pubmed ID

26186374

DOI

10.1097/ICO.0000000000000531

Scopus ID

2-s2.0-84939804615 (requires institutional sign-in at Scopus site)   53 Citations

Abstract

PURPOSE: The purpose of this study was to describe the results of a simple 6-mm central descemetorhexis in eyes with Fuchs corneal endothelial dystrophy.

METHODS: This prospective nonrandomized IRB approved pilot study was performed on 2 patients with coexisting Fuchs dystrophy and cataract who underwent combined phacoemulsification and descemetorhexis without endothelial transplantation.

RESULTS: In each patient, residual disciform stromal edema corresponded to the diameter of the descemetorhexis and led to an associated loss of visual acuity. Vision improved to 20/40 -1 in case 1 and to 150 -1 in case 2 during a follow-up period of 12 and 10 months, respectively. Endothelial cell repopulation of the descemetorhexis could not be confirmed because of the presence of persistent corneal edema.

CONCLUSIONS: Because of the relatively poor postoperative visual acuity and slow visual recovery, a simple descemetorhexis is not an acceptable form of therapy for eyes with Fuchs corneal endothelial dystrophy.

Author List

Koenig SB

MESH terms used to index this publication - Major topics in bold

Aged
Cataract
Corneal Pachymetry
Corneal Topography
Descemet Membrane
Endothelium, Corneal
Fuchs' Endothelial Dystrophy
Humans
Lens Implantation, Intraocular
Male
Phacoemulsification
Pilot Projects
Prospective Studies
Visual Acuity