Polyamines and other accessory sex gland secretions in human seminal plasma 8 years after vasectomy. J Reprod Fertil 1989 Sep;87(1):39-45
Date
09/01/1989Pubmed ID
2621711DOI
10.1530/jrf.0.0870039Scopus ID
2-s2.0-0024450791 (requires institutional sign-in at Scopus site) 23 CitationsAbstract
In 56 males, vasectomized 8 years previously, and in 56 age-matched non-vasectomized controls, a number of secretory products of prostatic, seminal vesicular and epididymal/testicular origin were used to monitor post-operative changes in accessory sex gland function. Significant reductions were observed in seminal plasma volume (3.0 vs 4.9 ml, P less than 0.01), and the total ejaculate contents of zinc (5.1 vs 9.7 mumol, P less than 0.01), magnesium (10.6 vs 26.5 mumol, P less than 0.01), PAP (371 vs 1260 IU, P less than 0.005) and citric acid (76.7 vs 127.9 mumol, P less than 0.05), indicating a major impact on secretions of prostatic origin. Unaltered PGE-1 (54.3 vs 53.2 micrograms, P less than 0.95) and fructose (3.9 vs 4.5 mumol, P greater than 0.1) indicated no effects on the secretory function of the seminal vesicles. A marked reduction was demonstrated in the ejaculatory contents of the polyamines, spermidine (366 vs 650 nmol, P less than 0.005) and spermine (5435 vs 11 804 nmol, P less than 0.05) but not their acknowledged precursor, putrescine, which is also of prostatic origin.
Author List
Jakobsen H, Rui H, Thomassen Y, Hald T, Purvis KMESH terms used to index this publication - Major topics in bold
Acid PhosphataseAdult
Aged
Citrates
Citric Acid
Cross-Sectional Studies
Genitalia, Male
Humans
Magnesium
Male
Middle Aged
Postoperative Period
Prostate
Putrescine
Semen
Spermidine
Spermine
Vasectomy
Zinc
