Faculty Collaboration Database

Synchronous presentation of ampullary adenocarcinoma and common bile duct cancer: report of a case and review of literature. JOP 2012 Sep 10;13(5):536-9

Date

09/12/2012

Pubmed ID

22964962

DOI

10.6092/1590-8577/836

Scopus ID

2-s2.0-84866431160 (requires institutional sign-in at Scopus site)   5 Citations

Abstract

CONTEXT: Ampullary adenocarcinomas and bile duct cancers represent a very small minority of all gastrointestinal malignancies. Synchronous presentation of both malignancies is extremely rare.

CASE REPORT: We report a case of a 76-year-old male who presented with painless jaundice. His work-up showed an ampullary mass and a separate common bile duct stricture. Attempted endoscopic resection established the diagnosis of ampullary adenocarcinoma. Pathologic examination of the Whipple specimen identified a separate focus of bile duct cancer.

CONCLUSION: Synchronous presentation of an ampullary mass and separate distal bile duct stricture, especially in elderly patients, should raise concern for both lesions representing malignancies. In the absence of conclusive evidence for survival advantage in resected early stage ampullary and biliary cancers, close observation should be considered a valid alternative to adjuvant chemotherapy and radiation.

Author List

Wohlauer MV, McManus MC, Brauer B, Hedges J, Gajdos C

MESH terms used to index this publication - Major topics in bold

Adenocarcinoma
Aged
Ampulla of Vater
Common Bile Duct Neoplasms
Diagnosis, Differential
Duodenal Neoplasms
Female
Humans
Male
Neoplasms, Multiple Primary