Anesthetic management of a parturient with Stiff person syndrome for urgent cesarean delivery. Int J Obstet Anesth 2016 Aug;27:85-8
Date
07/06/2016Pubmed ID
27378710DOI
10.1016/j.ijoa.2016.05.006Scopus ID
2-s2.0-84990964653 (requires institutional sign-in at Scopus site) 2 CitationsAbstract
Stiff person syndrome is a rare neurologic disorder with an estimated incidence of 1:1000000. The underlying pathophysiology is truncal and proximal limb muscle stiffness resulting from continuous co-contracture of agonist and antagonist muscle groups concomitant with superimposed episodic muscle spasms. Loss of gamma-aminobutyric acid-mediated inhibition creates chronic excitation manifested by tonic agonist-antagonist muscle contraction. To date, only three case reports referred indirectly to the anesthetic management of parturients with Stiff person syndrome. The authors describe their management of a parturient with Stiff person syndrome who underwent urgent cesarean delivery under epidural anesthesia.
Author List
Boettcher BT, Muravyea M, Kuo C, Drexler C, Pagel PSAuthor
Brent Boettcher DO Associate Professor in the Anesthesiology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultAnesthesia, Epidural
Anesthesia, Obstetrical
Cesarean Section
Emergencies
Female
Humans
Pregnancy
Stiff-Person Syndrome
