Faculty Collaboration Database

Ovarian-Sparing Surgery in Pediatric Benign Ovarian Tumors. J Pediatr Adolesc Gynecol 2016 Oct;29(5):506-510

Date

04/16/2016

Pubmed ID

27079914

DOI

10.1016/j.jpag.2016.03.009

Scopus ID

2-s2.0-84978966766 (requires institutional sign-in at Scopus site)   37 Citations

Abstract

STUDY OBJECTIVE: To evaluate outcomes of children after ovarian-sparing surgery (OSS) for non-neoplastic and benign neoplastic ovarian lesions.

DESIGN: Retrospective cohort study from January 2003 to January 2012.

SETTING: Single, high-volume, tertiary care hospital.

PARTICIPANTS: Children 18 years of age and younger.

INTERVENTIONS: None.

MAIN OUTCOME MEASURES: Postoperative complications and tumor recurrence after OSS.

RESULTS: One hundred nine patients underwent OSS with a median age of 13.3 years (interquartile range [IQR], 11.4-15.1 years). Eighty-two patients were treated laparoscopically with 4 conversions to an open procedure. Postoperative complications included surgical site infections in 7 patients (6%). Pathology most commonly revealed functional ovarian cysts (n = 57) and mature teratomas (n = 37). Ninety-four patients (86%) were followed for a median of 10.4 months (IQR, 0.72-30.8 months). Fifty-five patients (60%) had subsequent imaging surveillance a median of 7.6 months postoperatively (IQR, 3.9-13 months). Ten patients (10%) developed a second ipsilateral lesion within a median time of 11 months (IQR, 7.7-24 months), of whom 5 girls had repeated surgery for mass enlargement or persistent abdominal pain at a median time of 10.5 months (IQR, 8.0-12.65 months). Fifty-eight patients (63%) began or resumed menses at their most recent follow-up. Three girls became pregnant after OSS at a median follow-up of 5 years (range, 2.4-6.7 years).

CONCLUSION: Benign ovarian lesions in children can be treated successfully with OSS with low recurrence and repeat surgery rates.

Author List

Abbas PI, Dietrich JE, Francis JA, Brandt ML, Cass DL, Lopez ME

Author

Jessica Francis MD Associate Professor in the Obstetrics and Gynecology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adolescent
Child
Cohort Studies
Female
Humans
Laparoscopy
Neoplasm Recurrence, Local
Organ Sparing Treatments
Ovarian Neoplasms
Ovary
Pediatrics
Postoperative Complications
Pregnancy
Reoperation
Retrospective Studies
Treatment Outcome