Epidemiology of Peripheral Arterial Disease and Critical Limb Ischemia. Tech Vasc Interv Radiol 2016 Jun;19(2):91-5
Date
07/18/2016Pubmed ID
27423989DOI
10.1053/j.tvir.2016.04.001Scopus ID
2-s2.0-84973920731 (requires institutional sign-in at Scopus site) 211 CitationsAbstract
With a rise in the aging popluation, the prevalence of peripheral arterial disease (PAD) is markedly increasing. The overall disease prevalence of PAD is in the range of 3%-10%, which increases to 15%-20% in persons older than 70 years of age. Given this upward trend in disease prevalence, the economic and societal burden of PAD would be considerable. The subgroup of patients who develop critical limb ischemia (CLI) represents the most challenging population to manage medically, surgically, and endovascularly. Patients with symptomatic PAD and CLI have an increased risk for death and cardiovascular events, especially in those with CLI who carry with them a substantial risk of limb loss. Advances in medical, surgical, and endovascular techniques have shown excellent outcomes in the treatment of these patients, however the optimal management paradigm has not been elucidated. This article reviews the classification and epidemiology, risk factors, natural history, and health care costs associated with PAD and CLI.
Author List
Dua A, Lee CJMESH terms used to index this publication - Major topics in bold
AdultAge Distribution
Aged
Asymptomatic Diseases
Critical Illness
Endovascular Procedures
Female
Health Care Costs
Humans
Incidence
Ischemia
Limb Salvage
Lower Extremity
Male
Middle Aged
Peripheral Arterial Disease
Prevalence
Risk Factors
Time Factors
Treatment Outcome
Vascular Surgical Procedures
