Synchronous Tumors: Adenocarcinoma of the Esophagus and Clear Cell Renal Carcinoma. Conn Med 2015 Aug;79(7):401-4
Date
09/29/2015Pubmed ID
26411176Scopus ID
2-s2.0-84940653430 (requires institutional sign-in at Scopus site)Abstract
Synchronous cancers in patients with esophageal cancer are rare. We present a female nonsmoker with gastrointestinal symptoms that led to the diagnosis of HER-2/neu positive esophageal adenocarcinoma. During the staging workup, she was found to have a synchronous early-stage clear cell renal carcinoma. The patient underwent an esophagogastrectomy and radical nephrectomy and remains disease-free at a 12-month follow-up visit. We offer a detailed literature review on esophageal cancer and second primary malignancies seen in this context. Our case is unique as the literature suggests more advanced staging at diagnosis and poorer prognosis in persons with synchronous or metachronous cancers of esophagus and kidney. We believe that studies involving more patients are needed for the long-term prognosis assessment in these patients.
Author List
Narra RK, Alvarez Argote J, Mesologites T, Dasanu CAAuthors
Juliana Alvarez Argote MD Assistant Professor in the Medicine department at Medical College of WisconsinRavi Kishore Narra MD Assistant Professor in the Medicine department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
AdenocarcinomaBiopsy
Carcinoma, Renal Cell
Diagnosis, Differential
Esophageal Neoplasms
Esophagectomy
Female
Humans
Kidney Neoplasms
Laparoscopy
Middle Aged
Neoplasm Staging
Neoplasms, Multiple Primary
Nephrectomy
Tomography, X-Ray Computed
