Faculty Collaboration Database

Official Positions for FRAX® clinical regarding smoking from Joint Official Positions Development Conference of the International Society for Clinical Densitometry and International Osteoporosis Foundation on FRAX®. J Clin Densitom 2011;14(3):190-3

Date

08/04/2011

Pubmed ID

21810524

DOI

10.1016/j.jocd.2011.05.011

Scopus ID

2-s2.0-79960928988 (requires institutional sign-in at Scopus site)   15 Citations

Abstract

The worldwide prevalence of smoking has been estimated at about 50% in men, and 10% in women, with larger variations among different populations studied. Smoking has been shown to affect many organ systems resulting in severe morbidity and increased mortality. In addition, smoking has been identified as a predictor of ten-year fracture risk in men and women, largely independent of an individual's bone mineral density. This finding has eventually lead to incorporation of this risk factor into FRAX®, an algorithm that has been developed to calculate an individual's ten-year fracture risk. However, only little, or conflicting data is available on a possible association between smoking dose, duration, length of time after cessation, type of tobacco and fracture risk, limiting this risk factor's applicability in the context of FRAX®.

Author List

Dimai HP, Chandran M, FRAX(®)Position Development Conference Members

MESH terms used to index this publication - Major topics in bold

Absorptiometry, Photon
Algorithms
Diagnosis, Computer-Assisted
Female
Fractures, Bone
Humans
Male
Models, Statistical
Osteoporotic Fractures
Risk Assessment
Risk Factors
Smoking
Smoking Cessation