Medical College of Wisconsin
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Primary leiomyosarcoma of the thyroid gland. Thyroid 2008 Apr;18(4):425-8

Date

03/19/2008

Pubmed ID

18346004

DOI

10.1089/thy.2007.0276

Scopus ID

2-s2.0-42049093024 (requires institutional sign-in at Scopus site)   31 Citations

Abstract

Primary leiomyosarcomas of the thyroid gland are rare. We present the case of a 65-year-old woman with a rapidly enlarging neck mass for 2 months. The preoperative differential diagnosis included medullary thyroid cancer, anaplastic thyroid cancer, and primary versus metastatic sarcoma. The patient underwent total thyroidectomy, bilateral central neck dissections, and cervical thymectomy; she is currently being treated with ifosfamide and adriamycin. We review the literature on leiomyosarcoma of the thyroid, including the differential diagnoses, pathology, and alternative treatment strategies, including surgery and adjuvant therapy.

Author List

Wang TS, Ocal IT, Oxley K, Sosa JA

Author

Tracy S. Wang MD, MPH Professor in the Surgery department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Aged
Biopsy, Fine-Needle
Female
Humans
Immunohistochemistry
Leiomyosarcoma
Necrosis
Neoplasm Metastasis
Thyroid Gland
Thyroid Neoplasms
Thyroidectomy
Tomography, X-Ray Computed
Treatment Outcome