Individual differences in brain responses to cigarette-related cues and pleasant stimuli in young smokers. Drug Alcohol Depend 2016 Jun 01;163:229-35
Date
05/05/2016Pubmed ID
27141838Pubmed Central ID
PMC4880545DOI
10.1016/j.drugalcdep.2016.04.025Scopus ID
2-s2.0-84969134503 (requires institutional sign-in at Scopus site) 10 CitationsAbstract
BACKGROUND: Decreased sensitivity to pleasant stimuli is associated with a higher vulnerability to nicotine dependence in youths and with difficulty quitting in adult smokers. Recently, we showed that smokers showing lower brain reactivity to non-cigarette-related pleasant images than to cigarette-related ones have lower chances of achieving long-term abstinence during a quit attempt.
METHODS: We tested whether individual differences in brain responses to cigarette-related and pleasant stimuli require a long history of smoking to develop by measuring the late positive potential (LPP) to cigarette cues, emotional, and neutral stimuli in 45 young, light smokers (ages 18-25). k-means cluster analysis was used to partition smokers into two groups based on the magnitude of their LPPs.
RESULTS: Group 1 was characterized by larger LPPs to pleasant pictures than cigarette-related pictures whereas Group 2 showed the opposite pattern.
CONCLUSIONS: Our results suggest that individual differences in brain responses to cigarette-related and pleasant cues do not require a long smoking history to develop.
Author List
Engelmann JM, Versace F, Gewirtz JC, Cinciripini PMMESH terms used to index this publication - Major topics in bold
AdolescentAdult
Brain
Cues
Emotions
Evoked Potentials
Female
Humans
Individuality
Male
Photic Stimulation
Pleasure
Smoking
Smoking Cessation
Tobacco Products
Tobacco Use Disorder
Young Adult
