The hypereosinophilic syndrome: analysis of fourteen cases with review of the literature. Medicine (Baltimore) 1975 Jan;54(1):1-27
Date
01/01/1975Pubmed ID
1090795Scopus ID
2-s2.0-0016430025 (requires institutional sign-in at Scopus site) 1272 CitationsAbstract
Several closely related disease entities make up the idiopathic hypereosinophilic syndrome (HES). The syndrome is manifest by persistent and prolonged eosinophilia with organ damage. A group of 14 patients had hematologic, cardiac, and neurologic abnormalities attributable to this disease. Patient survival and response to chemotherapy was significantly better in this group than in previously reported patients. The etiology of HES remains unknown, as does the mechanism of tissue damage.
Author List
Chusid MJ, Dale DC, West BC, Wolff SMMESH terms used to index this publication - Major topics in bold
AdolescentAdult
Age Factors
Aged
Cardiovascular Diseases
Child
Child, Preschool
Eosinophilia
Eosinophils
Female
Hematopoietic System
Humans
Kidney Diseases
Leukemia
Liver Diseases
Lung Diseases
Male
Middle Aged
Neurologic Manifestations
Prognosis
Pulmonary Eosinophilia
Sex Factors
Skin Manifestations
Steroids
