Smartphone based optical spectrometer for diffusive reflectance spectroscopic measurement of hemoglobin. Sci Rep 2017 Sep 22;7(1):12224
Date
09/25/2017Pubmed ID
28939898Pubmed Central ID
PMC5610341DOI
10.1038/s41598-017-12482-5Scopus ID
2-s2.0-85029756433 (requires institutional sign-in at Scopus site) 93 CitationsAbstract
We report a miniature, visible to near infrared G-Fresnel spectrometer that contains a complete spectrograph system, including the detection hardware and connects with a smartphone through a microUSB port for operational control. The smartphone spectrometer is able to achieve a resolution of ~5 nm in a wavelength range from 400 nm to 1000 nm. We further developed a diffuse reflectance spectroscopy system using the smartphone spectrometer and demonstrated the capability of hemoglobin measurement. Proof of concept studies of tissue phantoms yielded a mean error of 9.2% on hemoglobin concentration measurement, comparable to that obtained with a commercial benchtop spectrometer. The smartphone G-Fresnel spectrometer and the diffuse reflectance spectroscopy system can potentially enable new point-of-care opportunities, such as cancer screening.
Author List
Edwards P, Zhang C, Zhang B, Hong X, Nagarajan VK, Yu B, Liu ZAuthor
Bing Yu PH.D. Assistant Professor of Biomedical Engineering in the Biomedical Engineering department at Marquette UniversityMESH terms used to index this publication - Major topics in bold
HemoglobinsHumans
Phantoms, Imaging
Point-of-Care Systems
Smartphone
Spectrophotometry
