Treatment of diffuse large B-cell lymphoma of the liver with yttrium-90 microsphere embolization. Nat Clin Pract Oncol 2008 Nov;5(11):677-81
Date
09/18/2008Pubmed ID
18797436DOI
10.1038/ncponc1227Scopus ID
2-s2.0-55549109367 (requires institutional sign-in at Scopus site) 1 CitationAbstract
BACKGROUND: A 41-year-old male with a 4-year history of chronic hepatitis C presented with a 1-month history of abdominal pain, fatigue, weight loss, and night sweats.
INVESTIGATIONS: Laboratory examinations, chest, abdomen, and pelvic CT scans, PET-CT scans, ultrasound-guided needle biopsies of liver lesions, bone-marrow biopsy, flow cytometry, and immunohistochemical staining for B-cell markers including CD20.
DIAGNOSIS: Chemoresistant diffuse large B-cell lymphoma, with gradual loss of CD20 antigen expression.
MANAGEMENT: Embolization of hepatic tumors using yttrium-90 microspheres (Therasphere, Theragenics Corporation, Buford, GA).
Author List
Fenske TS, Benjamin H, Kroft SH, Hohenwalter EJ, Rilling WSAuthors
Eric J. Hohenwalter MD, FSIR Chief, Professor in the Radiology department at Medical College of WisconsinSteven Howard Kroft MD Chair, Professor in the Pathology department at Medical College of Wisconsin
William S. Rilling MD, FSIR Vice Chair, Professor in the Radiology department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
AdultAntigens, CD20
Biomarkers, Tumor
Biopsy
Diagnosis, Differential
Embolization, Therapeutic
Fatal Outcome
Humans
Liver Neoplasms
Lymphoma, Large B-Cell, Diffuse
Male
Microspheres
Palliative Care
Yttrium Radioisotopes
