Bariatric surgery as a treatment for heart failure: review of the literature and potential mechanisms. Surg Obes Relat Dis 2018 Jan;14(1):117-122
Date
11/08/2017Pubmed ID
29108893Pubmed Central ID
PMC5748002DOI
10.1016/j.soard.2017.09.534Scopus ID
2-s2.0-85032968849 (requires institutional sign-in at Scopus site) 58 CitationsAbstract
Heart failure due to severe obesity is a complex disease due to multiple mechanisms, including increased body mass, inflammation, and impaired cardiac metabolism that is complicated by obesity-associated co-morbidities, such as type 2 diabetes and obstructive sleep apnea. Bariatric surgery significantly improves cardiac geometry, function, and symptoms related to obesity cardiomyopathy. There is a consistently positive impact of bariatric surgery on diastolic function with the potential to significantly improve systolic function as measured by ejection fraction in patients with advanced heart failure. For end-stage heart failure patients, including those requiring mechanical circulatory support who are ineligible for organ transplant due to morbid obesity, bariatric surgery has been successfully used for weight loss as a bridge to cardiac transplantation.
Author List
Kindel TL, Strande JLAuthor
Tammy Lyn Kindel MD, PhD Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Bariatric SurgeryCardiomyopathies
Diabetes Mellitus, Type 2
Heart Failure
Heart Transplantation
Humans
Obesity, Morbid
Sleep Apnea Syndromes
Time-to-Treatment
Treatment Outcome
