Test for carcinogenicity of metallic compounds by the pulmonary tumor response in strain A mice. Cancer Res 1976 May;36(5):1744-7
Date
05/01/1976Pubmed ID
1268831Scopus ID
2-s2.0-0017194811 (requires institutional sign-in at Scopus site) 125 CitationsAbstract
The production of lung adenomas in strain A mice following multiple i.p. injections of 13 metallic compounds was investigated. A significant increase in the average number of lung tumors per mouse was noted following the administration of lead subacetate, manganous sulfate, molybdenum trioxide, and nickelous acetate. These four compounds can be considered as weakly carcinogenic for lung tumors in strain A mice.
Author List
Stoner GD, Shimkin MB, Troxell MC, Thompson TL, Terry LSMESH terms used to index this publication - Major topics in bold
AdenomaAnimals
Female
Lead
Lung Neoplasms
Male
Manganese Poisoning
Metals
Mice
Molybdenum
Neoplasms, Experimental
Nickel
Urethane
