Simultaneous detection of seven sexually transmitted agents in human immunodeficiency virus-infected Brazilian women by multiplex polymerase chain reaction. Am J Trop Med Hyg 2013 Dec;89(6):1199-202
Date
10/02/2013Pubmed ID
24080632Pubmed Central ID
PMC3854900DOI
10.4269/ajtmh.13-0315Scopus ID
2-s2.0-84890411961 (requires institutional sign-in at Scopus site) 28 CitationsAbstract
We determined the prevalence of seven clinically important pathogens that cause sexually transmitted infections (STIs) (Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Trichomonas vaginalis, herpes simplex virus 1 [HSV-1], HSV-2, and Treponema pallidum), by using a multiplex polymerase chain reaction (M-PCR) in samples from Brazilian woman infected with human immunodeficiency virus 1 (HIV-1) and uninfected Brazilian women (controls). The M-PCR assay identified all STIs tested for and surprisingly, occurred association between the control and STIs. This association was probably caused by excellent HIV infection control and regular monitoring in these women established by public health strategies in Brazil to combat HIV/acquired immunodeficiency syndrome. Studies using this M-PCR in different populations may help to better elucidate the roles of STIs in several conditions.
Author List
Souza RP, de Abreu AL, Ferreira ÉC, Rocha-Brischiliari SC, de B Carvalho MD, Pelloso SM, Bonini MG, Gimenes F, Consolaro MEMESH terms used to index this publication - Major topics in bold
AdultBrazil
Chlamydia trachomatis
DNA Primers
Female
HIV Infections
Herpesvirus 1, Human
Herpesvirus 2, Human
Humans
Middle Aged
Multiplex Polymerase Chain Reaction
Mycoplasma genitalium
Neisseria gonorrhoeae
Prevalence
Sexually Transmitted Diseases
Treponema pallidum
Trichomonas vaginalis
