What everybody should know about the rat genome and its online resources. Nat Genet 2008 May;40(5):523-7
Date
04/30/2008Pubmed ID
18443589Pubmed Central ID
PMC2505193DOI
10.1038/ng0508-523Scopus ID
2-s2.0-42649114445 (requires institutional sign-in at Scopus site) 39 CitationsAbstract
It has been four years since the original publication of the draft sequence of the rat genome. Five groups are now working together to assemble, annotate and release an updated version of the rat genome. As the prevailing model for physiology, complex disease and pharmacological studies, there is an acute need for the rat's genomic resources to keep pace with the rat's prominence in the laboratory. In this commentary, we describe the current status of the rat genome sequence and the plans for its impending 'upgrade'. We then cover the key online resources providing access to the rat genome, including the new SNP views at Ensembl, the RefSeq and Genes databases at the US National Center for Biotechnology Information, Genome Browser at the University of California Santa Cruz and the disease portals for cardiovascular disease and obesity at the Rat Genome Database.
Author List
Twigger SN, Pruitt KD, Fernández-Suárez XM, Karolchik D, Worley KC, Maglott DR, Brown G, Weinstock G, Gibbs RA, Kent J, Birney E, Jacob HJMESH terms used to index this publication - Major topics in bold
AnimalsComputational Biology
Databases, Genetic
Disease Models, Animal
Genetic Diseases, Inborn
Genetic Variation
Genome
Genomics
Haplotypes
Humans
Internet
Polymorphism, Single Nucleotide
Rats
Rats, Mutant Strains
Sequence Analysis, DNA
