Genetics: An integrated genetic analysis of disease. Nat Rev Nephrol 2018 May;14(5):287-288
Date
04/10/2018Pubmed ID
29629715Pubmed Central ID
PMC6800230DOI
10.1038/nrneph.2018.26Scopus ID
2-s2.0-85045577194 (requires institutional sign-in at Scopus site)Abstract
A recent GWAS of quantitative traits (clinical lab measurements) was performed and incorporated with additional GWAS of a variety of complex diseases in Japanese subjects. Together, the data demonstrated pleiotropy, genetic correlation, and cell type specificity in regard to quantitative disease traits as predictors of multiple complex diseases.
Author List
Mattson DLMESH terms used to index this publication - Major topics in bold
AdultCell Lineage
Disease
Female
Genetic Association Studies
Genetic Predisposition to Disease
Genetic Testing
Genetics, Population
Genome-Wide Association Study
Humans
Japan
Male
Multifactorial Inheritance
Phenotype
Polymorphism, Single Nucleotide
Quantitative Trait Loci
Sequence Analysis, DNA
