Accuracy of computed tomography in diagnosing malignancy in solitary pulmonary lesions. J Pak Med Assoc 2011 Jan;61(1):48-51
Date
03/01/2012Pubmed ID
22368902Scopus ID
2-s2.0-78651261394 (requires institutional sign-in at Scopus site) 3 CitationsAbstract
OBJECTIVE: To evaluate accuracy of Computed Tomography (CT) for diagnosing malignancy in solitary pulmonary lesions (SPLs).
METHODS: A prospective cross-sectional study was conducted from 20-01-2007 to 30-06-2008 at the Radiology department, Aga Khan University Hospital (AKUH) Karachi. Fifty-three patients with solitary pulmonary lesions (SPLs) seen in prior chest x-rays or chest CT scans were referred to radiology department for CT guided biopsy. CT scan was performed for each patient prior to biopsy and CT evaluation of the SPLs was performed followed by CT guided Biopsy. Histopathological diagnosis of the lesion was taken as the gold standard.
RESULTS: CT was found to be 100% sensitive, 30% specific and 87% accurate for diagnosing malignancy in solitary pulmonary lesions while PPV and NPV were 86% and 100% respectively.
CONCLUSION: CT scan is highly sensitive yet non-specific and cannot be used as the definitive diagnostic modality for diagnosing malignancy in solitary pulmonary lesions.
Author List
Imaad-ur-Rehman, Memon W, Husen Y, Akhtar W, Sophie R, Baig MAMESH terms used to index this publication - Major topics in bold
AdultAged
Aged, 80 and over
Biopsy, Needle
Cross-Sectional Studies
Female
Humans
Lung
Lung Neoplasms
Male
Middle Aged
Prospective Studies
Sensitivity and Specificity
Solitary Pulmonary Nodule
Tomography, X-Ray Computed
Young Adult
