Mesh term Cytochrome P-450 CYP3A
Browse to parent terms:Cytochrome P450 Family 3
Oxidoreductases, N-Demethylating
Description
A cytochrome P-450 suptype that has specificity for a broad variety of lipophilic compounds, including STEROIDS; FATTY ACIDS; and XENOBIOTICS. This enzyme has clinical significance due to its ability to metabolize a diverse array of clinically important drugs such as CYCLOSPORINE; VERAPAMIL; and MIDAZOLAM. This enzyme also catalyzes the N-demethylation of ERYTHROMYCIN.Search for this term in our Faculty Database
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