Medical College of Wisconsin
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Deborah M. Costakos BS, MS, MD

Deborah M. Costakos BS, MS, MD profile photo picture

Dean, Professor

Institution: Medical College of Wisconsin
Department: Ophthalmology

Member of the Center for Disease Prevention Research (CDPR)

View Curriculum Vitae

Publications (35)

  • GJA8-associated developmental eye disorders: a new multicentre study highlights mutational hotspots and genotype-phenotype correlations (Merepa SS, Reis LM, Damián A, Bardakjian T, Schneider A, Trujillo-Tiebas MJ, Ayuso C, Galarza LC, Saez Villaverde R, Ortiz-Cabrera NV, Bax DA, Holt R, Ceroni F, Edery P, Grelet M, Riccardi F, Maillard L, Costakos D, Plaisancié J, Chassaing N, Corton M, Semina EV, Ragge NK) European Journal of Human Genetics July 2025;33(7):860-869 SCOPUS ID: 2-s2.0-105003803205 07/01/2025       4 Citations
  • Secondary glaucoma after bevacizumab injection in Type-1 retinopathy of prematurity (Jones AA, Martin JS, Giangiacomo AL, Costakos DM) American Journal of Ophthalmology Case Reports December 2024;36 SCOPUS ID: 2-s2.0-85199504850 12/01/2024    
  • Congenital anterior segment ocular disorders: Genotype-phenotype correlations and emerging novel mechanisms. (Reis LM, Seese SE, Costakos D, Semina EV) Prog Retin Eye Res 2024 Sep;102:101288 PMID: 39097141 PMCID: PMC11392650 SCOPUS ID: 2-s2.0-85200800135 08/04/2024       13 Citations
  • In Vivo Assessment of Retinal Phenotypes in Axenfeld-Rieger Syndrome. (Untaroiu A, Reis LM, Higgins BP, Walesa A, Zacharias S, Nikezic D, Costakos DM, Carroll J, Semina EV) Invest Ophthalmol Vis Sci 2024 Apr 01;65(4):20 PMID: 38587439 PMCID: PMC11005067 SCOPUS ID: 2-s2.0-85190399640 04/08/2024       2 Citations
  • Quantitative Foveal Structural Metrics as Predictors of Visual Acuity in Human Albinism. (Woertz EN, Ayala GD, Wynne N, Tarima S, Zacharias S, Brilliant MH, Dunn TM, Costakos D, Summers CG, Strul S, Drack AV, Carroll J) Invest Ophthalmol Vis Sci 2024 Mar 05;65(3):3 PMID: 38441889 PMCID: PMC10916884 SCOPUS ID: 2-s2.0-85186846764 03/05/2024       6 Citations
  • Association between myopia progression and quantity of laser treatment for retinopathy of prematurity. (Hwang ES, Kassem IS, Allozi R, Kravets S, Al-Kirwi KY, Hallak JA, Costakos DM) PLoS One 2022;17(12):e0279898 PMID: 36584135 PMCID: PMC9803142 SCOPUS ID: 2-s2.0-85145425573 12/31/2022       8 Citations
  • Axenfeld-Rieger syndrome: more than meets the eye. (Reis LM, Maheshwari M, Capasso J, Atilla H, Dudakova L, Thompson S, Zitano L, Lay-Son G, Lowry RB, Black J, Lee J, Shue A, Kremlikova Pourova R, Vaneckova M, Skalicka P, Jedlickova J, Trkova M, Williams B, Richard G, Bachman K, Seeley AH, Costakos D, Glaser TM, Levin AV, Liskova P, Murray JC, Semina EV) J Med Genet 2023 Apr;60(4):368-379 PMID: 35882526 PMCID: PMC9912354 SCOPUS ID: 2-s2.0-85135137847 07/27/2022       53 Citations
  • Eye Disorders (Costakos DM) Nelson Pediatric Symptom Based Diagnosis Common Diseases and their Mimics 1 January 2022:784-817.e2 SCOPUS ID: 2-s2.0-85199044141 01/01/2022    
  • Decorin Concentrations in Aqueous Humor of Patients with Diabetic Retinopathy. (Low SWY, Vaidya T, Gadde SGK, Mochi TB, Kumar D, Kassem IS, Costakos DM, Ahmad B, Sethu S, Ghosh A, Chaurasia SS) Life (Basel) 2021 Dec 17;11(12) PMID: 34947953 PMCID: PMC8707400 SCOPUS ID: 2-s2.0-85122401745 12/25/2021       8 Citations
  • Syphilitic interstitial keratitis treated with topical tacrolimus (Martin J, Kopplin L, Costakos D) American Journal of Ophthalmology Case Reports September 2021;23 SCOPUS ID: 2-s2.0-85111879851 09/01/2021       5 Citations
  • Small leucine-rich proteoglycans (Slrps) in the retina (Low SWY, Connor TB, Kassem IS, Costakos DM, Chaurasia SS) International Journal of Molecular Sciences 2 July 2021;22(14) SCOPUS ID: 2-s2.0-85109111419 07/02/2021       29 Citations
  • Dominant variants in PRR12 result in unilateral or bilateral complex microphthalmia (Reis LM, Costakos D, Wheeler PG, Bardakjian T, Schneider A, Fung SSM, Semina EV) Clinical Genetics March 2021;99(3):437-442 SCOPUS ID: 2-s2.0-85097633599 03/01/2021       14 Citations
  • Examining whether aoslo-based foveal cone metrics in achromatopsia and albinism are representative of foveal cone structure (Litts KM, Woertz EN, Wynne N, Brooks BP, Chacon A, Connor TB, Costakos D, Dumitrescu A, Drack AV, Fishman GA, Hauswirth WW, Kay CN, Lam BL, Michaelides M, Pennesi ME, Stepien KE, Strul S, Summers CG, Carroll J) Translational Vision Science and Technology 2021;10(6) SCOPUS ID: 2-s2.0-85106940811 01/01/2021       8 Citations
  • Dominant variants in PRR12 result in unilateral or bilateral complex microphthalmia. (Reis LM, Costakos D, Wheeler PG, Bardakjian T, Schneider A, Fung SSM, University of Washington Center for Mendelian Genomics, Semina EV) Clin Genet 2021 Mar;99(3):437-442 PMID: 33314030 PMCID: PMC8259391 SCOPUS ID: 2-s2.0-85097633599 12/15/2020       14 Citations
  • Utilizing Electronic Medical Records to Standardized Handoffs in Academic Ophthalmology (Sun,Lynn W, Stahulak, Andrea L, Costakos, Deborah M) Journal of Academic Ophthalmology JAO-170R1 10/30/2020    
  • An Overview of the Crystallized Structures of the SARS-CoV-2. (Ionescu MI) Protein J 2020 Dec;39(6):600-618 PMID: 33098476 PMCID: PMC7584483 SCOPUS ID: 2-s2.0-85093922788 10/25/2020       40 Citations
  • Survey of practice patterns for the management of ophthalmic genetic disorders among AAPOS members: report by the AAPOS Genetic Eye Disease Task Force. (Drack AV, Miraldi Utz V, Wang K, Alcorn DM, Brooks BP, Costakos DM, Couser NL, Heon E, Levin AV, Lloyd IC, Morse CL, Schmitt MA, Whitman MC, Traboulsi EI) J AAPOS 2019 Aug;23(4):226-228.e1 PMID: 31233830 SCOPUS ID: 2-s2.0-85071356353 06/25/2019       7 Citations
  • Surgical Timing for Congenital Ptosis Should Not Be Determined Solely by the Presence of Anisometropia. (Chisholm SAM, Costakos DM, Harris GJ) Ophthalmic Plast Reconstr Surg 2019;35(4):374-377 PMID: 30789542 SCOPUS ID: 2-s2.0-85069292061 02/23/2019       14 Citations
  • Reply. (Costakos DM, Vogel R, Carroll J) Ophthalmology 2018 Aug;125(8):e57 PMID: 30032804 SCOPUS ID: 2-s2.0-85049633109 07/24/2018    
  • Findings in Persistent Retinopathy of Prematurity. (Warren CC, Young JB, Goldberg MR, Connor TB, Kassem IS, Costakos DM) Ophthalmic Surg Lasers Imaging Retina 2018 Jul 01;49(7):497-503 PMID: 30021036 PMCID: PMC6196355 SCOPUS ID: 2-s2.0-85050358307 07/19/2018       12 Citations
  • Nelson Pediatric Symptom-Based Diagnosis Chapter 32, Eye Disorders (D.M. Costakos) 11/29/2017    
  • Foveal Development in Infants Treated with Bevacizumab or Laser Photocoagulation for Retinopathy of Prematurity. (Vogel RN, Strampe M, Fagbemi OE, Visotcky A, Tarima S, Carroll J, Costakos DM) Ophthalmology 2018 Mar;125(3):444-452 PMID: 29103792 SCOPUS ID: 2-s2.0-85034963642 11/07/2017       47 Citations
  • Histopathological analysis of retinopathy of prematurity after intravitreal bevacizumab. (Bee CR, Burris CKH, Potter HAD, Reddy D, Simons KB, Costakos DM) J AAPOS 2017 Apr;21(2):159-160 PMID: 28219740 SCOPUS ID: 2-s2.0-85017181489 02/22/2017    
  • Eye Disorders (Costakos DM) Nelson Pediatric Symptom Based Diagnosis 1 January 2017:563-593.e2 SCOPUS ID: 2-s2.0-85054348122 01/01/2017    
  • Analysis of CYP1B1 in pediatric and adult glaucoma and other ocular phenotypes. (Reis LM, Tyler RC, Weh E, Hendee KE, Kariminejad A, Abdul-Rahman O, Ben-Omran T, Manning MA, Yesilyurt A, McCarty CA, Kitchner TE, Costakos D, Semina EV) Mol Vis 2016;22:1229-1238 PMID: 27777502 PMCID: PMC5070572 SCOPUS ID: 2-s2.0-85008178877 10/26/2016       18 Citations
  • Case report of homozygous deletion involving the first coding exons of GCNT2 isoforms A and B and part of the upstream region of TFAP2A in congenital cataract. (Happ H, Weh E, Costakos D, Reis LM, Semina EV) BMC Med Genet 2016 Sep 08;17(1):64 PMID: 27609212 PMCID: PMC5016880 SCOPUS ID: 2-s2.0-84986296839 09/10/2016       8 Citations
  • ATTENUATION OF THE GANGLION CELL LAYER IN A PREMATURE INFANT REVEALED WITH HANDHELD SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY. (Goldberg MR, Zakka FR, Carroll JJ, Costakos DM) Retin Cases Brief Rep 2016;10(3):229-31 PMID: 26529438 PMCID: PMC4853294 SCOPUS ID: 2-s2.0-84973279045 11/04/2015       2 Citations
  • Relationship between foveal cone specialization and pit morphology in albinism. (Wilk MA, McAllister JT, Cooper RF, Dubis AM, Patitucci TN, Summerfelt P, Anderson JL, Stepien KE, Costakos DM, Connor TB Jr, Wirostko WJ, Chiang PW, Dubra A, Curcio CA, Brilliant MH, Summers CG, Carroll J) Invest Ophthalmol Vis Sci 2014 May 20;55(7):4186-98 PMID: 24845642 PMCID: PMC4098060 SCOPUS ID: 2-s2.0-84904346942 05/23/2014       119 Citations
  • Bilateral Acute Retinal Necrosis with Concurrent Retinopathy of Prematurity in Two Neonates. (LaMattina KC, Wirostko WJ, Costakos DM) Ocul Immunol Inflamm 2016;24(1):115-7 PMID: 24830465 SCOPUS ID: 2-s2.0-84957966343 05/17/2014       6 Citations
  • Subclinical macular findings in infants screened for retinopathy of prematurity with spectral-domain optical coherence tomography. (Dubis AM, Subramaniam CD, Godara P, Carroll J, Costakos DM) Ophthalmology 2013 Aug;120(8):1665-71 PMID: 23672969 PMCID: PMC3737379 SCOPUS ID: 2-s2.0-84881190253 05/16/2013       86 Citations
  • Whole exome sequencing in dominant cataract identifies a new causative factor, CRYBA2, and a variety of novel alleles in known genes. (Reis LM, Tyler RC, Muheisen S, Raggio V, Salviati L, Han DP, Costakos D, Yonath H, Hall S, Power P, Semina EV) Hum Genet 2013 Jul;132(7):761-70 PMID: 23508780 PMCID: PMC3683360 SCOPUS ID: 2-s2.0-84879499591 03/20/2013       88 Citations
  • Evaluation of normal human foveal development using optical coherence tomography and histologic examination. (Dubis AM, Costakos DM, Subramaniam CD, Godara P, Wirostko WJ, Carroll J, Provis JM) Arch Ophthalmol 2012 Oct;130(10):1291-300 PMID: 23044942 PMCID: PMC3724218 SCOPUS ID: 2-s2.0-84867365423 10/10/2012       104 Citations
  • Bilateral central retinal artery occlusions in an infant with hyperhomocysteinemia. (Karth P, Singh R, Kim J, Costakos D) J AAPOS 2012 Aug;16(4):398-400 PMID: 22819238 SCOPUS ID: 2-s2.0-84865488803 07/24/2012       23 Citations
  • Chronic myelogenous leukemia manifested as bilateral proliferative retinopathy. (Mandava N, Costakos D, Bartlett HM) Arch Ophthalmol 2005 Apr;123(4):576-7 PMID: 15824241 SCOPUS ID: 2-s2.0-16844373517 04/13/2005       25 Citations
  • Dural Fistulas. (Costakos DM, Bennett JL) Curr Treat Options Neurol 2001 Jul;3(4):377-382 PMID: 11389807 06/08/2001    
    • Last update: 12/11/2025