Medical College of Wisconsin
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CURRICULUM VITAE

Allison D. Ebert PhD
Associate Professor
Department of Cell Biology, Neurobiology and Anatomy

OFFICE ADDRESS:
Medical Education Building
8701 Watertown Plank Rd
Milwaukee, WI 53226

EDUCATION:
08/1995 - 05/1999 B.A. Chemistry, Indiana University, Bloomington, IN
08/1995 - 05/1999 B.A. Psychology, Indiana University, Bloomington, IN
09/1999 - 06/2005 Ph.D., Northwestern University, Chicago, IL

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
09/2004 - 06/2007 Post-doctoral fellow, Stem Cell Research Program, University of Wisconsin-Madison, Madison, WI
06/2007 - 10/2009 Assistant Scientist, Department of Neurology, Stem Cell and Regenerative Medicine Center, University of Wisconsin, Madison, WI
10/2009 - 12/2010 Associate Scientist, Department of Neurology, Stem Cell and Regenerative Medicine Center, University of Wisconsin, Madison, WI

FACULTY APPOINTMENTS:
01/2011 - 06/2018 Assistant Professor, Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI
01/2011 - Present Member, Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, WI
07/2015 - Present Interim Director, Program in Regenerative Medicine and Stem Cell Biology, Medical College of Wisconsin, Milwaukee, WI
08/2015 - Present Primary Member, Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI
07/2018 - Present Associate Professor, Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI

AWARDS AND HONORS:
05/1999 Phi Beta Kappa
11/2003 Pre-doctoral Travel Award, Children's Memorial Medical Research Council
05/2004 Pre-doctoral Research Seminar Participant, St. Jude Research Hospital
05/2006 Post-doctoral Travel Award, American Society for Neural Therapy and Repair
09/2007 Young Neuroscientists' Workshop Participant, Children's Neurobiological Solutions
2014 - 2015 Outstanding Medical Student Teacher-Medical Neurosciences, Medical College of Wisconsin
2014 - 2015 Outstanding Medical Student Teacher-Physician Scientist Pathway, Medical College of Wisconsin
2016 - 2017 Outstanding Medical School Educator-Physician Scientist Pathway
2016 - 2017 Outstanding Graduate School Educator-Neuroscience Program

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
Society for Neuroscience
American Association for the Advancement of Science
International Society for Stem Cell Research

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Editorship
Co-Editor of Encyclopedia for Stem Cell Research
Editorial Board
Genes (Section for Human Genomics and Genetic Diseases)
Journal Review
Cell Science
Nature
Cell Transplantation
Journal of Comparative Neurology
Journal of Neuroscience
Journal of Neuroscience Research
Stem Cells
Neuroscience
Neuroscience Letters
Human Molecular Genetics
PLoS One
Molecular Therapy
Stem Cell Reports
Experimental Neurology

LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
07/2015 - Present Member, Leadership Team, ALS Association Wisconsin Chapter

NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS:
10/2011 Early Career Reviewer, Neurogenesis and Cell Fate Study Section, NIH
02/2012 Reviewer for NYSTEM program, Scientific Peer Advisory and Review Services, American Institute of Biological Sciences
02/2013 Reviewer for NYSTEM Program, Scientific Peer Advisory and Review Services, American Institute of Biological Sciences
02/2015 Ad Hoc Reviewer, R13/U13 Conference and Scientific Meeting Review Panel, NIH/NIGMS
03/2015 Ad Hoc Reviewer, Peer Review Committee, NASA Human Exploration Research Opportunities
10/2015 Ad Hoc Reviewer, Neurogenesis and Cell Fate Study Section, NIH
02/2016 Ad Hoc Reviewer, Bioengineering of Neuroscience, Vision, and Low Vision Technologies Study Section, NIH
05/2016 Letter of Intent Reviewer, International Scientific Committee Member, AriSLA- Italian ALS Association
09/2016 Reviewer for NYSTEM Program, Scientific Peer Advisory and Review Services, American Institute of Biological Sciences
05/2017 - 11/2017 Letter of Intent, Full Application, and Consensus Meeting Reviewer (conducted in Milan, Italy Nov 2017), International Scientific Committee Member, AriSLA-Italian ALS Association
10/2017 Ad Hoc Reviewer, Cellular and Molecular Biology of Glia, NIH

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
MicroRNAs and anesthetic-induced developmental neurotoxicity
Source:
NIH/NIGMS
Role:
Co-Investigator
PI:
Xiaowen Bai
Dates:
05/2014 - 02/2019
 
Title:
Developing nicorandil and companion biomarkers for DMD cardiomyopathy therapy
Source:
NIH/NHLBI
Role:
Co-Investigator
PI:
Jennifer Strande
Dates:
02/2017 - 01/2021
 
Title:
Dissecting Protein Quality Control Pathways in ALS
Source:
AHW
Role:
Co-Investigator
PI:
Matthew Scaglione
Dates:
01/2018 - 12/2019
 
Title:
Role of astrocyte-produced miR-146a in SMA pathology
Source:
CureSMA
Role:
PI
PI:
Allison Ebert
Dates:
02/2018 - 01/2020
 
Title:
Mechanistic link between GATA factors, SMN, and astrocyte senescence in SMA
Source:
NIH/NINDS
Role:
PI
PI:
Allison Ebert
Dates:
06/2018 - 05/2020
 
Title:
Cytomegalovirus manipulation of functional cortical tissue development
Source:
NIH/NIAID
Role:
PI
PI:
Scott Terhune (MPI)
Dates:
07/2018 - 06/2022
 
Non-Peer Review
Title:
Parkinson's Disease Research
Role:
PI
PI:
Allison Ebert
Dates:
11/2011 - Present
 
Title:
Regenerative Medicine Research
Role:
PI
PI:
Allison Ebert
Dates:
01/2018 - Present
 
Prior
Peer Review
Title:
General motor control mechanisms and disease training grant
Source:
NIH/NINDS
Role:
pre-doctoral fellow
PI:
D. James Surmeier
Dates:
2001 - 2003
 
Title:
Stem cell research training grant
Source:
NIH/NINDS
Role:
post-doctoral fellow
PI:
Clive Svendsen
Dates:
2006 - 2007
 
Title:
Motor neuron generation of SMA patient-derived pluripotent stem cells
Source:
NIH/CHHD R21
Role:
PI
PI:
Allison Ebert
Dates:
09/01/2009 - 08/31/2012
Direct Funds:
$275,000
 
Title:
Therapeutic Delivery Platforms against Botulism
Source:
NIH/NIAID R21/R33
Role:
Co-Investigator
PI:
Joseph T. Barbieri
Dates:
07/01/2012 - 06/30/2014
Direct Funds:
$420,000
 
Title:
Generation and characterization of ALS iPSC derived skeletal muscle
Source:
ALS Association
Role:
PI
PI:
Allison Ebert
Dates:
08/01/2012 - 07/31/2013
Direct Funds:
$40,000
 
Title:
Development and characterization of sensory neurons and Schwann cells from SMA iPSCs
Source:
MCW Research Affairs Committee
Role:
PI
PI:
Allison Ebert
Dates:
01/01/2013 - 06/30/2014
Direct Funds:
$25,000
 
Title:
Exploring cell specific mitochondrial function in neurological disease
Source:
Advancing a Healthier Wisconsin Redox Biology Sub-award
Role:
PI
PI:
Allison Ebert
Dates:
02/01/2014 - 01/31/2016
Direct Funds:
$10,000
 
Title:
Astrocytes and oxidative stress in SMA
Source:
Families of SMA
Role:
PI
PI:
Allison Ebert
Dates:
02/01/2014 - 01/31/2015
Direct Funds:
$95,000
 
Title:
NR2B transport in healthy and diseased iPSC-derived neurons
Source:
Advancing a Healthier Wisconsin
Role:
PI
PI:
Allison Ebert
Dates:
01/01/2015 - 12/31/2015
Direct Funds:
$25,000
 
Title:
Therapeutic effect of shRNA knockdown in Parkinson's disease iPSC-derived neurons
Source:
Neuroscience Research Center
Role:
PI
PI:
Allison Ebert
Dates:
07/2015 - 06/2016
Direct Funds:
$25,000
 
Title:
Systematic analysis of molecular pathways implicated in amyotrophic lateral sclerosis
Source:
Advancing a Healthier Wisconsin
Role:
PI
PI:
Allison Ebert
Dates:
07/2015 - 06/2017
Direct Funds:
$200,000
 
Non-Peer Review
Title:
Modeling neurodegenerative disease with stem cells
Source:
Advancing a Healthier Wisconsin
Role:
PI
PI:
Allison Ebert
Dates:
01/01/2011 - 09/30/2013
Direct Funds:
$400,000
 

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
Modeling spinal muscular atrophy with stem cells, MCW Developmental Biology Journal Club, Milwaukee, WI, 2011
Using stem cells to model and treat neurodegenerative diseases, MCW Physiology Department Seminar Series, Milwaukee, WI, 2012
Modeling neurodegenerative diseases with stem cells, MCW Pulmonary and Critical Care Research Retreat, Milwaukee, WI, 2012
Using stem cells to model and treat neurodegenerative disease, Marquette University Integrative Neuroscience Research Seminar, Milwaukee, WI, 2013
Stem Cell Research for Neurodegenerative Diseases, WI Neurological Society Annual Meeting, Pewaukee, WI, 2013
Opportunities and challenges of stem cell transplantation, MSTP Student Retreat, Delavan, WI, 2013
Annual Graduate Student Luncheon, Milwaukee, WI, 2014
Using induced pluripotent stem cells to model human disease, MCW Redox Biology Journal Club, Milwaukee, WI, 2014
Using iPSCs to understand the pathogenesis of spinal muscular atrophy, MCW Department of Biochemistry Seminar Series, Milwaukee, WI, 2014
Using stem cells to model neurodegenrative diseases, MCW Continuing Education Program: A Symposium for Senior Physicians, Milwaukee, WI, 2016
Parkinson's disease and neurodegenerative diseases, Froedtert & MCW Presidents' Advisory Council, Milwaukee, WI, 2016
Stem cells and human disease modeling, Women's Health Research Program, MCW Department of Obstetrics and Gynecology, Milwaukee, WI, 2016
Work-life balance strategies: Panel discussion, Advance: From Postdoc to Faculty, MCW Women's Faculty Council, Milwaukee, WI, 2016
Parkinson's disease modeling with iPSCs, Neuroscience Research Center Board Meeting, Milwaukee, WI, 2016
Modeling Parkinson's disease with iPSCs, MCW Presidents' Advisory Council Meeting, Milwaukee, WI, 2016
ALS and Basic Science Research, 13th Annual ALS Care and Research Symposium, Brookfield, WI, 2017
Using stem cells to model neurodegenerative diseases, MCW Neurology Grand Rounds, Milwaukee, WI, 2017
 
Regional
Stem cell transplantation for neurodegenerative diseases, UW-Madison Stem Cell Research Program Journal Club, Madison, WI, 2007
Ex vivo gene therapy in Parkinson's and Huntington's disease models, UW-Madison Anatomy Department Seminar Series, Madison, WI, 2008
Astrocyte-motor neuron interactions in SMA, Midwest Motoneuron Consortium, Indianapolis, IN, 2014
Using stem cells to model neurodegenerative diseases, UW-Madison Neurology Grand Rounds, Madison, WI, 2014
Role of astrocytes in SMA pathology, Emerging Technologies for Neurological Disorders, Northwestern University, Chicago, IL, 2014
Using stem cells to model neurodegenerative diseases, American Association of Anatomists, Milwaukee, WI, 2015
Structural and functional abnormalities in LRRK2 G2019S iPSC-derived sensory neurons, UW-Madison Stem Cell and Regenerative Medicine Center Seminar Series, Madison, WI, 2015
Astrocyte malfunction in SMA, Midwest Motoneuron Consortium, Indianapolis, IN, 2016
 
National
Modeling SMA with stem cells, Pediatric Orthopaedic Society of North America, Las Vegas, NV, 2009
Modeling SMA with stem cells, A. I. duPont Hospital for Children Research Seminar, Wilmington, DE, 2009
Generation and characterization of SMA iPSCs, FightSMA Annual Conference, Washtington DC, 2010
Using stem cells to model and treat neurodegenerative diseases, National Ataxia Foundation Conference, Chicago, IL, 2010
Mechanisms of motor neuron death in SMA iPSCs, FightSMA Annual Conference, Washington DC, 2011
Human stem cells and drug screening: Opportunities and challenges, Danaher Stem Cell Scientific Advisory Board, Washington DC, 2011
A stem cell model of spinal muscular atrophy, National Institute for Child Health and Development, Washington DC, 2011
Using stem cells to model and treat neurodegenerative diseases, Emory University, Atlanta, GA, 2012
Modeling neurodegenerative diseases in a dish, FightSMA Annual Conference, Washington DC, 2012
Role of glia in motor neuron loss in SMA, Indiana University School of Medicine, Indianapolis, IN, 2013
Modeling neuronal and glial function using disease-specific iPSCs, Challenges and opportunities in central nervous system regeneration, Hilton Head, SC, 2014
Oxidative stress and SMA, FightSMA Annual Conference, Washington DC, 2015
Methods for generating more purified astrocyte cultures from iPSCs, Creating Patient-specific Neural Cells for the In Vitro Study of Brain Disorders, The Banbury Center-Cold Spring Harbor Laboratory, NY, 2015
Evidence for astrocyte involvement and reactivity in SMA, CureSMA Annual Conference, Kansas City, MO, 2015
The astrocyte secretome in SMA, FightSMA Annual Conference, Washtington DC, 2016
In vitro modeling of neurodegenerative diseases, American Society of Neural Therapy and Repair, Clearwater Beach, FL, 2016
Aberrant GATA6 expression induces senescent-like phenotypes in iPSC-derived astrocytes, CureSMA Annual Meeting, Dallas, TX, 2018
Astrocyte dysfunction in spinal muscular atrophy, University of Connecticut Neuroscience Department Seminar Series, Storrs, Connecticut, 2018
 
International
Requirements for neurogenesis during division of neural progenitors, Spring School for Regenerative Medicine, Rostock, Germany, 2005
Isolation, growth, and manipulation of human neural progenitor cells, First Multidisciplinary Symposium on Stem Cells, Sao Paulo, Brazil, 2006
Human neural progenitor cells: A cell source for transplantation in neurodegenerative diseases, First Multidisciplinary Symposium on Stem Cells, Sao Paulo, Brazil, 2006
Human neural progenitor cells delivery GDNF in models of Parkinson's disease, Brazilian Federation of Experimental Biology Meeting, Águas de Lindóia, Brazil, 2007
Induced pluripotent stem cells from a spinal muscular atrophy patient, 10th Anniversary Japan Spinal Cord Foundation Symposium, Tokyo, Japan, 2009
Modeling CNS diseases using iPS cells, 6th International Stem Cell School in Regenerative Medicine, Odense, Denmark, 2009
Modeling CNS diseases using iPS cells, Biomedicine in the 21st Century, Rio de Janeiro, Brazil, 2009
Modeling neurodegenerative diseases using stem cells and reprogramming, VI Expert Meeting on Dementia, Madrid, Spain, 2009
Ex vivo gene therapy in Parkinson's and Huntington's disease models, 6th International Stem Cell School in Regenerative Medicine, Odense, Denmark, 2009
Using stem cells to model and treat neurodegenerative diseases, European Human Genetics Conference, Gothenburg, Sweden, 2010
Induced pluripotent stem cells for modeling neurological diseases, XXth World Congress of Neurology, Marrakesh, Morocco, 2011
SMN replacement in spinal muscular atrophy iPSCs, INGESTEM International Congress: Pluripotent stem cells: reprogramming and tissue engineering, Paris, France, 2015
Stem cell based modeling of neuromuscular diseases, 4th Ottawa International Conference on Neuromuscular Disease and Biology, Ottawa, Ontario, Canada, 2017
 

PEER REVIEWED WORKSHOPS/PRESENTATIONS:
National
Disease state dictates migration patterns of human neural progenitor cells, "Hot Topics in Stem Cell Biology" at Society for Neuroscience, Washington DC, 2005
Ex vivo gene delivery of GDNF in a primate model of Parkinson's disease, American Society for Neural Therapy and Repair Annual Meeting, Clearwater, FL, 2006
hNPCs over expressing GDNF or IGF reverse amphetamine induced rotations in a rat model of PD, Society for Neuroscience Annual Meeting, San Diego, CA, 2007
Using patient specific iPS cells to model brain and spinal cord neurodegenerative diseases, Minisymposia at Society for Neuroscience Annual Meeting, Chicago, IL, 2009
 

COMMITTEE SERVICE:
Medical College
12/2011 - Present Oral Qualifying Exam Committee, IDP
12/2011 - Present Oral Qualifying Exam Committee, Neuroscience Doctoral Program
01/2012 - Present Admissions Committee, Neuroscience Doctoral Program
09/2012 Neurology Department Research Grant Review Committee
06/2013 Research Strategy Work Group
2014 - Present Member, IDP Mentoring Committee, Graduate School
2014 - 2017 Member, Course Evaluation Committee, Graduate School
03/2016 - 04/2018 Vice-Chair, Institutional Biosafety Committee (IBC)
05/2018 - Present Chair, MCW Institutional Biosafety Committee (IBC)
 

MEDICAL COLLEGE TEACHING ACTIVITIES:
Medical Student Education
01/2012 - Present Medical Neuroscience Lab Staff
05/2014 - Present Medical Student Summer Research Mentor
2014 - Present Physician Scientist Pathway Small Group Facilitator
08/2015 - Present Lecturer-Molecules to Cells
08/2015 - Present Lecturer-Renal Respiratory Unit
 
Graduate Student Education
08/2012 - Present Developmental and Stem Cell Biology Instructor
01/2014 - Present Fundamentals of Neuroscience
01/2016 - Present Course director Neuroscience Journal Club
 

EXTRAMURAL TEACHING:
Community/Lay Public
2006 Madison East High School Biology Seminar (Madison, WI)
2007 Oakwood Village Retirement Community (Madison, WI)
2008 Sun Prairie Rotary Club (Sun Prairie, WI)
2008 UW-Madison Alumni Association Founders' Day (Kokomo, IN)
2008 UW-Madison Alumni Association Founders' Day (Dodgeville, WI)
2008 UW-Madison Alumni Association Day on Campus (Madison, WI)
2008 Kiwanis Club (Janesville, WI)
2009 Attic Angels Retirement Community (Madison, WI)
2009 Muskego High School Biology Seminar (Muskego, WI)
2009 Philanthropic Educational Organization (Madison, WI)
2009 Zor Shrine Club (Madison, WI)
2009 American Parkinson's Disease Association Patient Support Group (Madison, WI)
2010 MCW President's Breakfast Presentation (Milwaukee, WI)
2011 MCW Parkinson's Disease Symposium (Milwaukee, WI)
 
Graduate Student Education
01/2007 University of Coimbra, Department of Neuroscience, Coimbra, Portugal, Lecturer for Advanced Graduate Stem Cell course
08/2007 Federal University of São Paulo (UNIFESP), São Paulo, Brazil, Department of Neurophysiology, Instructor for Preclinical Models of Parkinson's Disease undergraduate and graduate seminar
08/2007 Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil, Department of Anatomy, Instructor for Preclinical Models of Parkinson's Disease undergraduate and graduate seminar
08/2007 BioPharmaceutical Technology Center Institute/Promega Corp, Madison, WI, Lecturer for Emerging Techniques in Protein and Genetic Engineering graduate course
08/2008 Royal Netherlands Academy of Arts and Sciences, Netherlands Institute of Neuroscience, Amsterdam, the Netherlands, Lecturer for the International Summer School of Brain Research graduate student and post-doctoral course
06/2009 BioPharmaceutical Technology Center Institute/Promega Corp, Madison, WI, Lecturer for Emerging Techniques in Protein and Genetic Engineering graduate course
 

MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED:
Medical Students
James Kleist, Medical College of Wisconsin, 2014 - 2015 Scholarly Project Mentor
Michael Meade, Medical College of Wisconsin, 2015 - 2016 Scholarly Project Mentor
Paraj Patel, Medical College of Wisconsin, 2016 - Present Scholarly Project Mentor
Brett Fulleylove-Krause, Medical College of Wisconsin, 2017 - Present Scholarly project Mentor
 
Graduate Students
PhD Committees
Kirk Twaroski, Medical College of Wisconsin, 03/2011 - 05/2015 Transient inhibition of canonical WNT signaling mediated by FGF2-induced expression of NKD1 is required for hepatic specification
Marie-Elizabeth Barabas, Medical College of Wisconsin, 11/2011 - 2014 Contribution of TRPA1 in postoperative mechanical allodynia
Megan Determan, Medical College of Wisconsin, 07/2012 - 06/2015 HNF1A-MODY int he human stem cell-derived hepatocyte-like cell
Bridget Kohlnhofer, Medical College of Wisconsin, 07/2012 - 02/2016 GATA4 is required for gastric mucosal development and intestinal growth and elogation
Danielle Twaroski, Medical College of Wisconsin, 02/2013 - 2015 Role of microRNAs and mitochondrial dynamics in propofol-induced neurotoxicity in developing human neurons
Tyler Lewis, Medical College of Wisconsin, 06/2013 - 10/2017 Microtubule motors in the ciliary photoreceptor
Anna Miller, Medical College of Wisconsin, 02/2014 - 07/2016 Organotypic Hippocampal Slice Cultures as an in Vitro Model to Study the Neuropathological Changes of Blast Traumatic Brain Injury and the Effects of Bone Marrow-Derived Mesenchymal Stem Cells
Erin Kropp, Medical College of Wisconsin, 03/2014 - 03/2016 Inhibition of NAMPT for Selective Elimination of Pluripotent Stem Cells: Defining Toxicity and Applications in Cardiomyocyte Differentiation
Katherine Zappia, Medical College of Wisconsin, 09/2014 - 05/2016 Role of TRP channels in sickle cell disease pain
Ryan Hillmer, Medical College of Wisconsin, 2014 - Present
Stephanie Santarriaga Escamilla, Medical College of Wisconsin, 04/2015 - Present
Joshua Nord, Medical College of Wisconsin, 04/2015 - Present
Eric Clark, Medical College of Wisconsin, 05/2015 - Present
Emily Gronseth, Medical College of Wisconsin, 09/2015 - Present
Michelle Storage, Medical College of Wisconsin, 07/2016 - Present
PhD Students Advised
Teresa Patitucci, Medical College of Wisconsin, 03/2011 - 02/2016 Astrocyte contribution to spinal muscular atrophy
Andrew Schwab, Medical College of Wisconsin, 05/2012 - 07/2016 Effect of LRRK2 G2019S mutation on iPSC-derived dopaminergic, glutamatergic and sensory neurons
Emily Seminary, Medical College of Wisconsin, 05/2015 - Present
MS Committees
Melanie Reiter, Medical College of Wisconsin, 2014 Nicorandil decreases oxidative stress in dystrophic iPSC-derived cardiomyocytes through NO/cGMP/AKT signaling
 
Clinical/Research Fellows
Jered McGivern, PhD, Medical College of Wisconsin, 01/2011 - 06/2014 Post-doctoral Fellow
 

EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED:
High School Students
Emily Levin, 2007 - 2008
Margaryta Bondarenko, 2007 - 2008
 
Undergraduate Students
Amy Beres, UW-Madison, 2004 - 2006
Brittany Heins, UW-Madison, 2007 - 2009
Timothy Pian, UW-Madison, 2008
Dan Krakora, UW-Madison, 2009 - 2010
Charles Hunter, 2011 SPUR participant
Hayley Powers, 2015 SPUR Participant
Sarah Erpenbeck, 2017 SPUR Participant
 

COMMUNITY SERVICE ACTIVITIES:
2016 Radio interview on WUWM Lake Effect Radio. http://wuwm.com/post/milwaukee-researcher-aids-effort-understand-als#stream/0
Wisconsin High School Leadership Seminar Speaker (Waukesha, WI, 2007)
Wenzel High School Science Conference Speaker at Marshfield Clinic (Marshfield, WI, 2009)
WiCell Research Institute Summer Science Camp Instructor (Madison, WI, 2009, 2008, 2007)
 

PATENTS:
07/03/2012 - 02/01/2030 US Issued Patent 8,211,631. In Vitro Model of Spinal Muscular Atrophy. C.N. Svendsen and A.D. Ebert


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Vavra M, Ali MJ, Kang EW, Navalitloha Y, Ebert A, Allen CV, Groothuis DR. Comparative pharmacokinetics of 14C-sucrose in RG-2 rat gliomas after intravenous and convection-enhanced delivery. Neuro Oncol. 2004 Apr;6(2):104-12. PMCID: PMC1871980
2. Ebert AD, Chen F, He X, Cryns VL, Bohn MC. A tetracycline-regulated adenovirus encoding dominant-negative caspase-9 is regulated in rat brain and protects against neurotoxin-induced cell death in vitro, but not in vivo. Exp Neurol. 2005 Feb;191 Suppl 1:S80-94.
3. Rick CE, Ebert A, Virag T, Bohn MC, Surmeier DJ. Differentiated dopaminergic MN9D cells only partially recapitulate the electrophysiological properties of midbrain dopaminergic neurons. Dev Neurosci. 2006;28(6):528-37.
4. Behrstock S, Ebert A, McHugh J, Vosberg S, Moore J, Schneider B, Capowski E, Hei D, Kordower J, Aebischer P, Svendsen CN. Human neural progenitors deliver glial cell line-derived neurotrophic factor to parkinsonian rodents and aged primates. Gene Ther. 2006 Mar;13(5):379-88.
5. Capowski EE, Schneider BL, Ebert AD, Seehus CR, Szulc J, Zufferey R, Aebischer P, Svendsen CN. Lentiviral vector-mediated genetic modification of human neural progenitor cells for ex vivo gene therapy. J Neurosci Methods. 2007 Jul 30;163(2):338-49.
6. Ebert AD, Beres AJ, Barber AE, Svendsen CN. Human neural progenitor cells over-expressing IGF-1 protect dopamine neurons and restore function in a rat model of Parkinson's disease. Exp Neurol. 2008 Jan;209(1):213-23.
7. Ebert AD, Hann HJ, Bohn MC. Progressive degeneration of dopamine neurons in 6-hydroxydopamine rat model of Parkinson's disease does not involve activation of caspase-9 and caspase-3. J Neurosci Res. 2008 Feb 01;86(2):317-25.
8. Emborg ME, Ebert AD, Moirano J, Peng S, Suzuki M, Capowski E, Joers V, Roitberg BZ, Aebischer P, Svendsen CN. GDNF-secreting human neural progenitor cells increase tyrosine hydroxylase and VMAT2 expression in MPTP-treated cynomolgus monkeys. Cell Transplant. 2008;17(4):383-95.
9. Behrstock S, Ebert AD, Klein S, Schmitt M, Moore JM, Svendsen CN. Lesion-induced increase in survival and migration of human neural progenitor cells releasing GDNF. Cell Transplant. 2008;17(7):753-62. PMCID: PMC2650839
10. Emborg ME, Moirano J, Raschke J, Bondarenko V, Zufferey R, Peng S, Ebert AD, Joers V, Roitberg B, Holden JE, Koprich J, Lipton J, Kordower JH, Aebischer P. Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF. Neurobiol Dis. 2009 Nov;36(2):303-11. PMCID: PMC2989601
11. Ebert AD, Yu J, Rose FF Jr, Mattis VB, Lorson CL, Thomson JA, Svendsen CN. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature. 2009 Jan 15;457(7227):277-80. PMCID: PMC2659408
12. Mattis VB, Ebert AD, Fosso MY, Chang CW, Lorson CL. Delivery of a read-through inducing compound, TC007, lessens the severity of a spinal muscular atrophy animal model. Hum Mol Genet. 2009 Oct 15;18(20):3906-13. PMCID: PMC2748896
13. Sareen D, McMillan E, Ebert AD, Shelley BC, Johnson JA, Meisner LF, Svendsen CN. Chromosome 7 and 19 trisomy in cultured human neural progenitor cells. PLoS One. 2009 Oct 29;4(10):e7630. PMCID: PMC2765070
14. Ebert AD, Barber AE, Heins BM, Svendsen CN. Ex vivo delivery of GDNF maintains motor function and prevents neuronal loss in a transgenic mouse model of Huntington's disease. Exp Neurol. 2010 Jul;224(1):155-62.
15. Jodelka FM, Ebert AD, Duelli DM, Hastings ML. A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2. Hum Mol Genet. 2010 Dec 15;19(24):4906-17. PMCID: PMC2989896
16. HD iPSC Consortium. Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeat-expansion-associated phenotypes. Cell Stem Cell. 2012 Aug 03;11(2):264-78. PMCID: PMC3804072
17. Sareen D, Ebert AD, Heins BM, McGivern JV, Ornelas L, Svendsen CN. Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy. PLoS One. 2012;7(6):e39113. PMCID: PMC3378532
18. Todd AG, Lin H, Ebert AD, Liu Y, Androphy EJ. COPI transport complexes bind to specific RNAs in neuronal cells. Hum Mol Genet. 2013 Feb 15;22(4):729-36. PMCID: PMC3988478
19. Ebert AD, Shelley BC, Hurley AM, Onorati M, Castiglioni V, Patitucci TN, Svendsen SP, Mattis VB, McGivern JV, Schwab AJ, Sareen D, Kim HW, Cattaneo E, Svendsen CN. EZ spheres: a stable and expandable culture system for the generation of pre-rosette multipotent stem cells from human ESCs and iPSCs. Stem Cell Res. 2013 May;10(3):417-427. PMCID: PMC3786426
20. McGivern JV, Patitucci TN, Nord JA, Barabas MA, Stucky CL, Ebert AD. Spinal muscular atrophy astrocytes exhibit abnormal calcium regulation and reduced growth factor production. Glia. 2013 Sep;61(9):1418-1428. PMCID: PMC3941074
21. Liegel RP, Handley MT, Ronchetti A, Brown S, Langemeyer L, Linford A, Chang B, Morris-Rosendahl DJ, Carpanini S, Posmyk R, Harthill V, Sheridan E, Abdel-Salam GM, Terhal PA, Faravelli F, Accorsi P, Giordano L, Pinelli L, Hartmann B, Ebert AD, Barr FA, Aligianis IA, Sidjanin DJ. Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans. Am J Hum Genet. 2013 Dec 05;93(6):1001-14. PMCID: PMC3852926
22. Schwab AJ, Ebert AD. Sensory neurons do not induce motor neuron loss in a human stem cell model of spinal muscular atrophy. PLoS One. 2014;9(7):e103112. PMCID: PMC4108398
23. Hosoyama T, McGivern JV, Van Dyke JM, Ebert AD, Suzuki M. Derivation of myogenic progenitors directly from human pluripotent stem cells using a sphere-based culture. Stem Cells Transl Med. 2014 May;3(5):564-74. PMCID: PMC4006483
24. Park AK, Liegel RP, Ronchetti A, Ebert AD, Geurts A, Sidjanin DJ. Targeted disruption of Tbc1d20 with zinc-finger nucleases causes cataracts and testicular abnormalities in mice. BMC Genet. 2014 Dec 05;15:135. PMCID: PMC4266191
25. Yu H, Fischer G, Ebert AD, Wu HE, Bai X, Hogan QH. Analgesia for neuropathic pain by dorsal root ganglion transplantation of genetically engineered mesenchymal stem cells: initial results. Mol Pain. 2015 Feb 12;11:5. PMCID: PMC4331376
26. Rindt H, Feng Z, Mazzasette C, Glascock JJ, Valdivia D, Pyles N, Crawford TO, Swoboda KJ, Patitucci TN, Ebert AD, Sumner CJ, Ko CP, Lorson CL. Astrocytes influence the severity of spinal muscular atrophy. Hum Mol Genet. 2015 Jul 15;24(14):4094-102. PMCID: PMC5007659
27. Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, Sawa A, Soldner F, Song H, Studer L, Temple S, Vaccarino FM, Wu J, Vanderhaeghen P, Gage FH, Jaenisch R. Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders. Stem Cell Reports. 2015 Dec 08;5(6):933-945. PMCID: PMC4881284
28. Schwab AJ, Ebert AD. Neurite Aggregation and Calcium Dysfunction in iPSC-Derived Sensory Neurons with Parkinson's Disease-Related LRRK2 G2019S Mutation. Stem Cell Reports. 2015 Dec 08;5(6):1039-1052. PMCID: PMC4682343
29. Patitucci TN, Ebert AD. SMN deficiency does not induce oxidative stress in SMA iPSC-derived astrocytes or motor neurons. Hum Mol Genet. 2016 Feb 01;25(3):514-23.
30. Bigley TM, McGivern JV, Ebert AD, Terhune SS. Impact of a cytomegalovirus kinase inhibitor on infection and neuronal progenitor cell differentiation. Antiviral Res. 2016 May;129:67-73. PMCID: PMC4957402
31. Osman EY, Washington CW 3rd, Kaifer KA, Mazzasette C, Patitucci TN, Florea KM, Simon ME, Ko CP, Ebert AD, Lorson CL. Optimization of Morpholino Antisense Oligonucleotides Targeting the Intronic Repressor Element1 in Spinal Muscular Atrophy. Mol Ther. 2016 09;24(9):1592-601. PMCID: PMC5113110
32. Afzal MZ, Reiter M, Gastonguay C, McGivern JV, Guan X, Ge ZD, Mack DL, Childers MK, Ebert AD, Strande JL. Nicorandil, a Nitric Oxide Donor and ATP-Sensitive Potassium Channel Opener, Protects Against Dystrophin-Deficient Cardiomyopathy. J Cardiovasc Pharmacol Ther. 2016 11;21(6):549-562. PMCID: PMC5010518
33. Sison SL, Patitucci TN, Seminary ER, Villalon E, Lorson CL, Ebert AD. Astrocyte-produced miR-146a as a mediator of motor neuron loss in spinal muscular atrophy. Hum Mol Genet. 2017 09 01;26(17):3409-3420.
34. Schwab AJ, Sison SL, Meade MR, Broniowska KA, Corbett JA, Ebert AD. Decreased Sirtuin Deacetylase Activity in LRRK2 G2019S iPSC-Derived Dopaminergic Neurons. Stem Cell Reports. 2017 12 12;9(6):1839-1852. PMCID: PMC5785678
35. Gray KM, Kaifer KA, Baillat D, Wen Y, Bonacci TR, Ebert AD, Raimer AC, Spring AM, Have ST, Glascock JJ, Gupta K, Van Duyne GD, Emanuele MJ, Lamond AI, Wagner EJ, Lorson CL, Matera AG. Self-oligomerization regulates stability of survival motor neuron protein isoforms by sequestering an SCF degron. Mol Biol Cell. 2018 01 15;29(2):96-110. PMCID: PMC5909936
36. Seminary ER, Sison SL, Ebert AD. Modeling Protein Aggregation and the Heat Shock Response in ALS iPSC-Derived Motor Neurons. Front Neurosci. 2018;12:86. PMCID: PMC5826239
37. Santarriaga S, Haver HN, Kanack AJ, Fikejs AS, Sison SL, Egner JM, Bostrom JR, Seminary ER, Hill RB, Link BA, Ebert AD, Scaglione KM. SRCP1 Conveys Resistance to Polyglutamine Aggregation. Mol Cell. 2018 07 19;71(2):216-228.e7. PMCID: PMC6091221
38. Sison SL, Vermilyea SC, Emborg ME, Ebert AD. Using Patient-Derived Induced Pluripotent Stem Cells to Identify Parkinson's Disease-Relevant Phenotypes. Curr Neurol Neurosci Rep. 2018 10 04;18(12):84. PMCID: PMC6739862
39. Logan S, Arzua T, Canfield SG, Seminary ER, Sison SL, Ebert AD, Bai X. Studying Human Neurological Disorders Using Induced Pluripotent Stem Cells: From 2D Monolayer to 3D Organoid and Blood Brain Barrier Models. Compr Physiol. 2019 03 14;9(2):565-611. PMCID: PMC6705133
40. Kaifer KA, Villalón E, O'Brien BS, Sison SL, Smith CE, Simon ME, Marquez J, O'Day S, Hopkins AE, Neff R, Rindt H, Ebert AD, Lorson CL. AAV9-mediated delivery of miR-23a reduces disease severity in Smn2B/-SMA model mice. Hum Mol Genet. 2019 Oct 01;28(19):3199-3210. PMCID: PMC6859438
41. Deguise MO, Patitucci TN, Ebert AD, Lorson CL, Kothary R. Contributions of Different Cell Types to Spinal Muscular Atrophy Pathogenesis Spinal Muscular Atrophy: Disease Mechanisms and Therapy. 4 November 2016:167-181.
42. McGivern JV, Ebert AD. Modelling neurodegenerative diseases using pluripotent stem cells Stem Cells and Cancer Stem Cells. 1 January 2012:421-430.
 
Books, Chapters, and Reviews
1. Ebert AD, Svendsen CN. A new tool in the battle against Alzheimer's disease and aging: ex vivo gene therapy. Rejuvenation Res. 2005;8(3):131-4.
2. Ebert AD, McMillan EL, Svendsen CN. Isolating, expanding, and infecting human and rodent fetal neural progenitor cells. Current Protocols in Stem Cell Biology. Chapter 2:Unit 2D.2. 2008.
3. Ebert AD, Svendsen CN. Stem cell model of spinal muscular atrophy. Arch Neurol. 2010 Jun;67(6):665-9. PMCID: PMC3140872
4. Ebert AD, Svendsen CN. Human stem cells and drug screening: opportunities and challenges. Nat Rev Drug Discov. 2010 05;9(5):367-72.
5. McGivern JV, Ebert AD. Modelling Neurodegenerative Diseases Using Pluripotent Stem Cells. M.A. Hayat (ed.), Stem Cells and Cancer Stem Cells, 2012, Vol 6. Ch. 37. 421-430.
6. McGivern JV, Ebert AD. Exploiting pluripotent stem cell technology for drug discovery, screening, safety, and toxicology assessments. Adv Drug Deliv Rev. 2014 Apr;69-70:170-8.
7. Rivero-Ríos P, Gómez-Suaga P, Fernández B, Madero-Pérez J, Schwab AJ, Ebert AD, Hilfiker S. Alterations in late endocytic trafficking related to the pathobiology of LRRK2-linked Parkinson's disease. Biochem Soc Trans. 2015 Jun;43(3):390-5.
8. Deguise M-O, Patitucci TN, Ebert AD, Lorson CL, Kothary R. Contributions of different cell types to spinal muscular atrophy pathogenesis. In: Spinal Muscular Atrophy: Disease Mechanisms and Therapy. Eds. Sumner, Paushkin, Ko. Elsevier Inc., 2017.
 
Editorials, Letters to Editor, Other
1. Ebert AD. Modeling neurodegenerative diseases using stem cells: Is it accelerating drug discovery? Future Med. Chem., 2012 4:1651-3.
2. Voss J, Ebert A, Wolfe M, Lindsley C, Cookson M, Deane R. The future of neurodegenerative diseases: emerging targets, treatments and technologies. Future Med Chem. 2012 Sep;4(13):1661-9.
3. Ebert AD. Modeling neurodegenerative diseases using stem cells: is it accelerating drug discovery? Future Med Chem. 2012 Sep;4(13):1651-3.
4. Sison SL, Ebert AD. Decreased NAD+ in dopaminergic neurons. Aging (Albany NY). 2018 Apr 28;10(4):526-527. PMCID: PMC5940114
 
Abstracts
1. A.D. Rufatto, M.C. Bohn (2002). Delivery of a dominant-negative caspase9 gene protects dopamine neurons against 6-OHDA. Society for Neuroscience, Orlando, FL
2. A.D. Ebert, M.C. Bohn (2003). Adenoviral vector delivery of a dominant-negative caspase9 gene or x-chromosome linked inhibitor of apoptosis protein gene each protect MN9D cells from 6-OHDA induced apoptosis. Society for Neuroscience, New Orleans, LA
3. M.C. Bohn, A.D. Ebert, L. Jiang, D. George, E.G. Bremer (2003). Effects of adenoviral vector mediated gene delivery of glial cell line-derived neurotrophic factor on gene expression profiles in substantia nigra of rats lesioned with 6-OHDA. Society for Neuroscience, New Orleans, LA
4. T. Virag, A.D. Ebert, C. Rick, M.C. Bohn, D.J. Surmeier (2003). Electrophysiological characterization of undifferentiated and differentiated MN9D cells. Society for Neuroscience, New Orleans, LA
5. A.D. Ebert, H.J. Hann, M.C. Bohn (2004). 6-OHDA induced death of dopaminergic cells involves caspase activation in vitro but not in vivo. Society for Neuroscience, San Diego, CA
6. A.D. Ebert, S. Behrstock, M. Schmitt, S. Klein, E. Capowski, C.N. Svendsen (2005). Disease state dictates migration patterns of human neural progenitor cells transplanted into the striatum. Society for Neuroscience, Washington, DC
7. M.C. Bohn, A.D. Ebert, J.W. Yates, M.K. Sapru (2006). Gene therapy approaches to protect DA neurons against cell death. World Parkinson's Congress, Washington DC
8. A.D. Ebert, A.E. Barber, C.N. Svendsen (2008). Glial cell line-derived neurotrophic factor ex vivo gene therapy in the N171-82Q transgenic mouse model of Huntington's disease. Society for Neuroscience, Washington, DC
9. D. Sareen, A.D. Ebert, C.N. Svendsen (2009). Extrinsic death receptor mediated apoptosis in motor neurons derived from iPS cells of a spinal muscular atrophy patient. Society for Neuroscience, Chicago, IL
10. B.C. Shelley, A.D. Ebert, B. Heins, J.V. McGivern, D. Sareen, C.N. Svendsen (2009). EZ spheres: a stable and expandable culture system for the generation of neural stem cells from hES and iPS cultures. Society for Neuroscience, Chicago, IL
11. A.D. Ebert, V.B. Mattis, A.E. Barber, J. Yu, J.A. Thomson, C.N. Svendsen (2009). Neuronal differentiation from induced pluripotent stem cells from Huntington's disease patients. Society for Neuroscience, Chicago, IL
12. K. Bernau, J.V. McGivern, B.C. Shelley, A.D. Ebert, I.J. Rowland, G. Gowing, B. L. Schneider, M. Suzuki, M.E. Meyerand, C.N. Svendsen (2010). In vivo tracking of human neural progenitor cells in rodent CNS via MR and optical imaging. World Molecular Imaging Congress, Kyoto, Japan.
13. V. B. Mattis, A. D. Ebert, J. Yu, S. Akimov, N. Arbez, A. Battersby, S. Brazier, V., et al, (2010) The HD consortium: effect of mutant huntingtin on striatal neurons differentiated from Huntington disease induced pluripotent stem cells. Society for Neuroscience, San Diego, CA
14. A.D. Ebert, D. Sareen, B.M. Heins, J.V. McGivern, C.N. Svendsen (2011). Rescue of SMA-iPSC derived motor neurons through apoptosis inhibition. Families of SMA, Orlando, FL
15. J.V. McGivern, T. Hosoyama, B.M. Heins, T.N. Patitucci, M. Suzuki, A.D. Ebert (2011). Generating skeletal muscle from induced pluripotent stem cells (IPSCs) derived from a patient with SMA. Families of SMA, Orlando, FL
16. A.G. Todd, H. Lin, N. Singh, A.D. Ebert, S. Custer, J. Cherry, Y. Liu, E. Androphy (2012). The RNA binding repertoire of the SMN-associated COPI transport vesicle. Families of SMA. Minneapolis, MN.
17. N. Miller, B. Yang, J.V. McGivern, H. Shi, M. Yang, A.D. Ebert, C.W. Cowan, Y.C. Ma (2012). Phosphorylation-dependent nuclear export of histone deacetylase 5 regulates motor neuron degeneration in spinal muscular atrophy. Families of SMA. Minneapolis, MN
18. J.V. McGivern, J. Nord, A.D. Ebert (2012). Increased astrocyte activation in both in vitro and in vivo models of SMA. Families of SMA. Minneapolis, MN
19. A.M. Hurley, B.C. Shelley, V. Castiglioni, S.P. Svendsen, V.B. Mattis, D. Sareen, H. Kim, B. Heins, J.V. McGivern, T.N. Patitucci, A.D. Ebert, E. Cattaneo, C.N. Svendsen (2012). EZ spheres: A comprehensive characterization of a stable and expandable culture system for neural stem cells derived from hESC and hiPSC cultures. Society for Neuroscience. New Orleans, LA
20. J.V. McGivern, T. Hosoyama, B.M. Heins, M. Suzuki, A.D. Ebert (2012). Building cellular circuits in vitro using iPSCs for neurodegenerative disease modeling. Society for Neuroscience. New Orleans, LA
21. TN Patitucci, JV McGivern, J Nord, ME Barabas, CL Stucky, AD Ebert (2012). Altered astrocyte function in both in vitro and in vivo models of Spinal Muscular Atrophy. Society for Neuroscience, New Orleans, LA
22. T.N. Patitucci, J.V. McGivern, J. Nord, M.E. Barabas, C.L. Stucky, A.D. Ebert (2012). Altered astrocyte function in models of Spinal Muscular Atrophy. MCW Faculty Research Day, Milwaukee, WI
23. J.V. McGivern, J. Van Dyke, T. Hosoyama, J. Strande, M. Suzuki, A.D. Ebert (2013). Modeling neuromuscular disease using skeletal muscle derived from disease specific induced pluripotent stem cell aggregate cultures (EZ spheres). International Society for Stem Cell Research. Boston, MA.
24. T.N. Patitucci, J.V. McGivern, J.A. Nord, M-E.A. Barabas, C.L. Stucky, A.D. Ebert (2013). Relationship of SMN to astrocyte activation in Spinal Muscular Atrophy. Families of SMA, Anaheim, CA. *Selected for poster highlight session
25. Emborg ME, Roitberg BZ, Moirano J, Zufferey R, Ebert AD, Joers V, Holden J, Converse AK, Koprich JB, Kordower JH, Aebischer P. Lentiviral Delivery of Glial Cell Line-derived Neurotrophic Factor in Aged 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated Rhesus Monkeys 883. Neurosurgery. 2006 Aug 01;59(2):481-482.
26. A.J. Schwab, M.E. Barabas, A.K. Smith, C.L. Stucky, A.D. Ebert (2013). Development and characterization of sensory neurons from Parkinson’s disease. Society for Neuroscience, San Diego, CA
27. T.N. Patitucci, J.V. McGivern, J. Nord, A.K. Smith, M.E. Barabas, C.L. Stucky, A.D. Ebert (2013). Involvement of PLC and ERK pathways in Spinal Muscular Atrophy astrocytes. Society for Neuroscience, San Diego, CA
28. A.J. Schwab, M.E. Barabas, A.K. Smith, C.L. Stucky, A.D. Ebert (2013). Development and characterization of sensory neurons from Parkinson’s disease. MCW research day, Milwaukee, WI
29. T.N. Patitucci, A.D. Ebert (2014). Non cell-autonomous effects of astrogliosis in Spinal Muscular Atrophy. Families of SMA Annual Meeting, Washington DC
30. A.J. Schwab, M.E. Barabas, A.K. Smith, C.L. Stucky, A.D. Ebert (2014). Morphological and functional deficits of Parkinson’s disease iPSC-derived sensory neurons. American Society for Neural Therapy and Repair, Clearwater, Fl
31. M.Z. Afzal, M. Reiter, C. Gastonguay, J. McGivern, A. Ebert, J. Strande (2014). Using iPCs with dystrophin gene mutations to compare differences in oxidative stress responses between cardiac and skeletal myocytes. New Directions in Biology and Disease of Skeletal Muscle Conference, Chicago, IL.
32. A.J. Schwab, A.D. Ebert (2014) Generation and characterization of SMA iPSC-derived sensory neurons. Families of SMA, Washington DC. *Selected for poster highlight session
33. A.J. Schwab, A.D. Ebert (2014). G2019S LRRK2 mutation elicits neurite aggregation and reduces calcium activity in iPSC-derived sensory neurons. MCW research day, Milwaukee, WI
34. L. Wang, M. Lepley, A. Ebert, D.R. Harder, R. Ramchandran (2015). Astrocytes in the microenvironment influence breast cancer cell metastasis. American Association for Cancer Research. Washington DC.
35. A.J. Schwab, M. Meade, A.D. Ebert (2015). Altered mitochondria function and trafficking in Parkinson’s disease iPSC-derived dopamine, sensory and glutamatergic neurons. MCW research day, Milwaukee, WI
36. A.J. Schwab, A.D. Ebert (2015). Effect of neurite aggregations and shortened neurites on mitochondrial and kinesin dynamics in Parkinson’s disease iPSC-derived sensory and dopamine neurons. American Society for Neural Therapy and Repair, Clearwater, Fl
37. T.N. Patitucci, K. Kalous, A.D. Ebert (2015). Oxidative stress in SMA iPSC-derived astrocytes and motor neurons. CureSMA Annual Meeting, Kansas City, MO
38. T.N. Patitucci, A.D. Ebert (2016). GDNF overexpression does not prevent astrocyte reactivity or motor neuron loss in an iPSC model of spinal muscular atrophy. CureSMA Annual Meeting, Anaheim, CA.
39. T.N. Patitucci, E.R. Seminary, A.D. Ebert. (2016) Differential microRNA expression from SMA iPSC-derived astrocytes. CureSMA Annual Meeting, Anaheim, CA.
40. S.L. Sison, T.N. Patitucci, E.R. Seminary, E. Villalon, C.L. Lorson, A.D. Ebert (2017). Astrocyte-produced miR-146a induces motor neuron loss in an iPSC model of SMA. CureSMA Annual Meeting, Orlando, FL *selected for poster highlight session
41. E.R. Seminary, S.L. Sison, A.D. Ebert. (2017). Upregulation of the heat shock protein response in ALS iPSC-derived motor neurons. 4th Ottawa International Conference on Neuromuscular Disease and Biology. Ottawa, Ontario, Canada.
42. E.R. Seminary, S.L. Sison, A.D. Ebert (2017). Modeling protein aggregation and the heat shock response in ALS iPSC-derived motor neurons. American Society of Cell Biology/European Molecular Biology Organization Annual Meeting. Philadelphia, PA
43. E.R. Seminary, S.L. Sison, A.D. Ebert (2017). Modeling protein aggregation and the heat shock response in ALS iPSC-derived motor neurons. MCW Graduate Student Research Symposium. Milwaukee, WI *poster award winner
 

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