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CURRICULUM VITAE

Joseph R. Cava MD, PhD
Associate Professor
Department of Pediatrics
Division of Cardiology

OFFICE ADDRESS:
Children's Hospital
9000 W Wisconsin Ave
Milwaukee, WI 53226

EDUCATION:
1978 - 1982 B.S., Marquette University, Milwaukee, WI
1983 - 1988 Ph.D., Marquette University, Milwaukee, WI
1990 - 1994 M.D., Loyola University, Maywood, IL

POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS:
1994 - 1997 Resident, Pediatrics, Medical College of Wisconsin, Children's Hospital of Wisconsin, Milwaukee, WI
1997 - 2000 Fellow, Pediatric Cardiology, Hope Children's Hospital, The Heart Institute for Children, Oak Lawn, IL
1998 - 1990 Postdoctoral Research Fellowship, University of Illinois at Chicago, Chicago, IL
2004 - 2005 Pediatric Cardiac MRI under direction of Dr. Tal Geva, Boston Children's Hospital, Boston, MA

FACULTY APPOINTMENTS:
07/2000 - 06/2008 Assistant Professor of Pediatrics, Pediatric Cardiology, Medical College of Wisconsin, Milwaukee, WI
07/2008 - Present Associate Professor of Pediatrics, Pediatric Cardiology, Medical College of Wisconsin, Milwaukee, WI

EDUCATIONAL ADMINISTRATIVE APPOINTMENTS:
2002 - 2004 Intern Select Committee, Medical College of Wisconsin, Milwaukee, WI
07/2004 - Present MCW Faculty Council Representative, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI

HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS:
08/2000 - Present Cardiologist - Outpatient Services, Pediatric Cardiology, Herma Heart Center, Children's Hospital of Wisconsin, Milwaukee, WI 53226
08/2000 - Present Cardiologist - Intensive Care and Inpatient Services, Pediatric Cardiology, Herma Heart Center, Children's Hospital of Wisconsin, Milwaukee, WI 53226
08/2000 - Present Echocardiographer, Pediatric Cardiology, Herma Heart Center, Children's Hospital of Wisconsin, Milwaukee, WI 53226
07/2005 - Present Director, Cardiac MRI Program, Pediatric Cardiology, Herma Heart Center, Children's Hospital of Wisconsin, Milwaukee, WI 53226

HOSPITAL STAFF PRIVILEGES:
07/2000 - Present Children's Hospital of Wisconsin, 9000 W. Wisconsin Avenue, Milwaukee, WI 53226
10/2000 - Present Froedtert Memorial Lutheran Hospital, 9200 W. Wisconsin Avenue, Milwaukee, WI 53226
12/2000 - 02/2018 Waukesha Memorial Hospital, 725 American Avenue, Waukesha, WI 53188
11/2001 - Present Children's Hospital of Wisconsin-Fox Valley, 640 Deerwood Avenue, Neenah, WI 54956
11/2001 - 12/2015 Thedaclark Medical Center, 130 2nd Street, Neenah, WI 54957
06/2002 - Present St. Vincent Hospital, 835 South Van Buren Street, Green Bay, WI 54307
11/2008 - 11/2010 Dickinson County Healthcare System, 1721 South Stephenson Avenue, Iron Mountain, MI 49801

SPECIALTY BOARDS AND CERTIFICATION:
Board Certified
Issue DateExpiration
American Board of Pediatrics
10/08/1997
None
American Board of Pediatrics - Cardiology
10/23/2007
None
 
Certificates
Issued By Issue DateExpiration
PALS
Children's Hospital of Wisconsin
01/2010
12/2018
BLS
Children's Hospital of Wisconsin
01/2010
12/2018
 

Licensure
Number Issue DateExpiration
Wisconsin License
36899-020
10/2019
Illinois License
036-095947
07/31/2011
Michigan License
4301093371
01/31/2012
Minnesota
1303
12/31/2009
 

AWARDS AND HONORS:
1983 - 1985 Teaching Assistantships, Marquette University
1985 - 1986 Tuition Scholarship, Marquette University
1987 Award for Biological Research, Pharmacia P-L Biochemicals
1994 Achievement Rewards for College Scientists (ARCS) Scholarship
1994 Alpha Omega Alpha Medical Honor Society
1997 Larrie B. Sarff Memorial Resident Teaching Award, Medical College of Wisconsin
1997 Senior Resident Pediatric Emergency Medicine Award, Medical College of Wisconsin

MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES:
1994 - Present American Academy of Pediatrics
1994 - Present Alpha Omega Alpha Medical Honor Society
2000 - Present Midwest Pediatric Cardiology Society
2002 - Present American College of Cardiology
2004 - Present Society for Cardiovascular Magnetic Resonance

EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS:
Editorial Board
Pediatric Cardiology
Journal Review
Invited Reviewer: American Journal of Cardiology Pediatrics - Annals of Thoracic Surgery

RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS:
Active
Peer Review
Title:
A Cardiac Magnetic Resonance Strain Imaging Study.
Source:
Children's Hospital of Wisconsin.
Role:
Co-investigator
Dates:
10/2007 - Present
 
Title:
Quantification of Cardiovascular Physiology Using Computational Simulations Created From Magnetic Resonance Imaging of Patients with Aortic Coarctation.
Source:
Children's Hospital of Wisconsin/Marquette University.
Role:
Co-Principal Investigator
Dates:
10/2007 - Present
 
Title:
Cardiac Magnetic Resonance Imaging Data Bank for Computational Fluid Dynamics Studies
Source:
Children's Hospital of Wisconsin/Marquette University.
Role:
Co-Principal Investigator
Dates:
2007 - Present
 
Title:
Comparison of Function in the Single Right Ventricle to Single Left Ventricle Following Fontan Operation
Source:
Children's Hospital of Wisconsin
Role:
Co-Investigator
Dates:
02/2009 - Present
 
Title:
Systemic Right Ventricular Characteristics in Fontan vs. Atrial Switch Patients
Source:
Children's Hospital of Wisconsin
Role:
Co-Investigator
Dates:
04/2009 - Present
 
Title:
Evaluation of Myocardial T1 Mapping and Extracellular Volume After Pediatric Heart Transplantation
Source:
CHW
Role:
Co-Investigator
Dates:
07/2016 - Present
 
Title:
Cardiac MRI Deformation Analysis in Patients with Single Ventricle Post Fontan Surgery
Source:
CHW
Role:
Co-Investigator
Dates:
07/2016 - Present
 
Title:
Hydrodynamic Evaluation of Arch Reconstruction in HLHS
Source:
CHW
Role:
Principle Investigator
Dates:
07/2018 - Present
 
Title:
Incorporation of Non-Invasive Magnet Resonance T2 Lymphatic Imaging as Part of risk Stratificaiton Prior to Fontan Operation
Source:
CHW
Role:
Co-Investigator
Dates:
07/2018 - Present
 
Prior
Peer Review
Title:
Rhizobium Lipopolysaccharide in legume nitrogen fixation
Source:
William Scholl Foundation, Dr. William Scholl Fellowship
Role:
Graduate Student Molecular Biology, Marquette
Dates:
1986 - 1988
 
Title:
Glucose Transporters in Endotoxic Shock
Source:
March of Dimes Birth Defects Foundation Research
Role:
Co-Investigator
Dates:
1991 - 1992
 
Title:
A study of the safety, tolerance and efficacy of Palivizumab (MEDI-493, Synagis) for prophylaxis of respiratory syncytial virus in children with congenital heart disease.
Source:
Med-Immune
Role:
Co-Investigator
Dates:
07/2000 - 08/2006
 
Title:
A Dose Response Study of the Efficacy, Safety, and Pharmacokinetics of Intravenous Amiodarone Hydrochloride in Pediatric Patients Thirty Days of Age to Sixteen Years of Age with Critical Arrhythmias. Protocol 0585K1-100275-US.
Source:
Wyeth-Ayerst Global Pharmaceuticals.
Role:
Principal Investigator
Dates:
12/2000 - 07/2001
 
Title:
Analysis of atrial natriuretic peptide, brain natriuretic peptide, and endothelin-1 in pediatric patients undergoing total cavopulmonary repair
Source:
Children's Hospital of Wisconsin
Role:
Principal Investigator
Dates:
07/2002 - 07/2004
 
Title:
A randomized, double blind study of regional vs. intravenous analgesia to promote early endotracheal extubation in children undergoing single ventricle palliation
Source:
Children's Hospital of Wisconsin/ Medical College of Wisconsin
Role:
Co-Investigator
Dates:
2002 - 2004
 
Title:
A multi-center, placebo-controlled 8-month study of the effect of twice daily carvedilol in children with congestive heart failure due to systemic ventricular systolic dysfunction.
Source:
GlaxoSmithKline/University of Utah
Role:
Co-Investigator
Dates:
2003 - 2005
 
Title:
Use of droperidol during cardiac anesthesia and its effects on the QT interval - a retrospective chart review
Source:
Children's Hospital of Wisconsin/ Medical College of Wisconsin
Role:
Co-Investigator
Dates:
2003
 
Title:
A randomized, multicenter, double blind, placebo-controlled, dose-ranging, parallel group study of intravenous Sildenafil in the treatment of children, aged 0-17 with pulmonary hypertension after cardiac surgery. Study 1481134
Source:
Pfizer
Role:
Co-Investigator
Dates:
03/2004 - 05/2006
 
Title:
A phase III, open-label, non-randomized, international, multicenter trail to evaluate the efficacy and safety of Cardiolite myocardial perfusion imaging in pediatric subjects with Kawasaki's disease
Source:
Bristol-Myers Squibb Medical Imaging
Role:
Co-Investigator
Dates:
2005 - 2007
 
Title:
A phase I-II, open-label, multi-center trial to determine the dosimetry and safety of technetium Tc99m Sestamibi in pediatric subjects. Protocol DuP 843-201
Source:
Bristol- Myers Squibb Medical Imaging
Role:
Principal Investiator
Dates:
2005 - 2007
 
Title:
Cardiac Magnetic Resonance Imaging Assessment of Early Atherosclerosis in Pediatric Patients with Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus, and Metabolic Syndrome
Source:
Children's Hospital of Wisconsin
Role:
Co-Investigator
Dates:
12/2007 - 07/2009
 
Title:
MRI Characteristics of Pediatric Cardiac Tumors
Source:
Children's Hospital of Wisconsin
Role:
Principal Investigator
Dates:
03/2009 - 07/2011
 
Title:
Incorporating the Aortic Valve into Patient-Specific CFD Models using Phase Contrast MRI and Valvular Gating
Source:
Children's Hospital of Wisconsin / Marquette University
Role:
Co-Investigator
Dates:
03/2009 - 07/2016
 
Title:
Quantification of Cardiovascular Physiology using Computational Simulations Created from Magnetic Resonance Imaging of Marfan Patients Before and After Aortic Root Replacement
Source:
Children's Hospital of Wisconsin
Role:
Co-Investigator
Dates:
05/2009 - 07/2015
 

INVITED LECTURES/WORKSHOPS/PRESENTATIONS:
Local
Cava, J.R., M. Goto, G. Leybovich, M. Sweet, W.P. Zeller, Glucose transporter isoform mRNA abundance changes in pancreatic islets of neonatal rats with endotoxic shock., St. Luke's Day Student Research Forum, Loyola University, Maywood, IL, 1991
Cava, J.R. Causes, Causes, risk factors, and therapies for hypercholesterolemia., Caring for Children with Heart Disease in the Community., Children's Hospital of Wisconsin, 2001
Cava, J.R., Cardiac Manifestations of Rheumatic Fever, Grand Rounds, Children's Hospital of Wisconsin, 2001
Cava, J.R., Cardiac Medications, Parent Education Day, Medical College of Wisconsin, 2002
Cava, J.R., Cardiac Medications, Parent Education Day, Medical College of Wisconsin, 2003
Cava, J.R., Cardiac Magnetic Resonance Imaging, Parent Education Day, Medical College of Wisconsin, 2005
Cava, J.R., Cardiac Magnetic Resonance in Congenital Heart Disease, Society of Critical Care Nursing, Milwaukee, WI, 2005
Cava, J.R., Cardiac Medications, Parent Education Day, Medical College of Wisconsin, 2006
Cava, J.R., Cardiac Magnetic Resonance Imaging, Grand Rounds, Children's Hospital of Wisconsin, 2007
Cava, J.R., Cardiac Magnetic Resonance Imaging in Adult Congenital Heart Disease, Cardiology Grand Rounds, Froedtert Memorial Lutheran Hospital, Milwaukee, WI, 2008
Cava, J.R., Magnetic Imaging of the Heart, Parent Education Day, Medical College of Wisconsin, 2010 - Present
Cava, JR., Cardiac Magnetic Resonance Imaging Tetrology of Fallot., Joint Adult-Pediatric CMR lecture series, Froedtert Memorial Lutheran Hospital, 2013
Cava, Jr., Cardiac Magnetic Resonance Imaging of the Fontan Patient, Joint Adult-Pediatric CMR lecture series, Froedtert Memorial Lutheran Hospital, 2014
Cava, J.R., Update on MRI QI, QI/Research Conference, Children's Hospital of Wisconsin, 09/19/2017
Cava, JR; Samyn, MM; Goot, BH; Gerardin, JF, Cardiac MRI Research - State of the Art, QI/Research Conference, Children's Hospital of Wisconsin, Herma Heart Institute, 09/25/2018
 
Regional
Cava J.R., Noel K.D., VandenBosch, K.A., Rhizobium phaseoli mutants defective in polysaccharide and infection thread induction., 10th North American Rhizobium Conference, Wailea, Maui, Hawaii, 1985
 
International
Cava JR, Pachori, PM, Turowski, DA, Noel, KD, Rhizobial lipopolysaccharide mutants: Genetic and symbiotic characterization., 7th International Conference on Nitrogen Fixation, Cologne, West Germany, 1988
A. Gordon BS, A. Punnoose MD, K. Yan PhD, B Goot MD, J.R. Cava MD PhD, M. Krolikowski MS, S. Kindel MD, and M. M. Samyn MD, Evaluation of Myocardial T1 Mapping and Extracellular Volume (ECV) After Pediatric Heart Transplantation., The Joint EuroCMR*/SCMR Meeting (CMR 2018), Barcelona, Spain, 01/31/2018 - 02/02/2018
 

CLINICAL PROGRAM DEVELOPMENT:
2004 Cardiac MRI: Development, implementation and advancement of Pediatric Cardiac Magnetic Resonance (CMR) Imaging program at Children’s Hospital of Wisconsin. Replacing diagnostic invasive procedures or ionizing radiation imaging with noninvasive, effective, and safer alternative.

EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED:
07/01/2006 - 06/30/2008 Rohit Rao, MD. Outpatient pediatric cardiology. Pediatric Cardiology Fellowship, MCW.
07/01/2007 - 06/30/2008 David Saudek, MD Fourth year noninvasive imaging fellow. Pediatric Cardiology Fellowship, Medical College of Wisconsin
2007 - 2013 John F. LaDisa, Ph.D. Computational analysis of fluid dynamics in coarctation of the aorta. NIH repayment program.
2009 David C. Wendell, BSEE. Doctoral dissertation committee member. Marquette University, Milwaukee, WI.
2009 - 2016 David C. Wendell, BSEE. Incorporating the aortic valve into patient-specific CFD models using phase contrast MRI and valvular gating. AHA research award.
07/01/2010 - 06/30/2011 Alicia Chaves, MD. Fourth year noninvasive imaging fellow. Pediatric Cardiology Fellowship - Medical College of Wisconsin.
07/01/2011 - 06/30/2012 Joseph Camarda, MD. Fourth year noninvasive imaging fellow. Pediatric Cardiology Fellowship. Medical College of Wisconsin.

MEDICAL COLLEGE TEACHING ACTIVITIES:
Medical Students Education: Preceptor in Pediatric Cardiology 1 third year student (M3) per month for 12 months 1-2 Fourth year medical students (M4) per month for 10 months Lecturer for core pediatric lecture series; annual lecture Ward Attending General Pediatrics; 4 students 1 month per year Pediatric Residents Education: Pediatric Cardiology Attending primary care (outpatient experience) 0-2 residents per month Ward attending in General Pediatrics 1 month per year 4 pediatric and/or family practice residents Lecturer for pediatric residents didactic lecture series Pediatric Cardiology Fellows Education: Attending Cardiologist for Fellowship program Lecturer for core lecture series CMR lecture series Hands on cardiac procedure instruction Training and supervision of direct patient care Pediatric Intensive Care Fellows Education: Attending Cardiologist for subspecialty training Lecturer combined core lecture series Direct patient care in intensive care unit Hands on cardiac procedure instruction Periodic didactic lectures for ICU team

PREVIOUS RESEARCH ACTIVITIES:
1988 Graduate Research: Molecular genetics and biochemistry of Rhizobial lipopolysaccharide were investigated. Research techniques included recombinant DNA technology, bacterial genetics, polyacrylamide gel electrophoresis, immunoblotting, gas/liquid chromatography for sugar analysis, and light and electron microscopy to analyze nodule structure.
1991 Medical School Research: The molecular biology of endotoxin induced septic shock in a neonatal rat model was investigated. Using cDNA probes, the mRNA isolated from pancreatic islets encoding glucose transporter proteins was identified and quantified.
1999 Postdoctoral Research: Experiments were designed to study the molecular biology of the E. coli chemotaxis system. Protein purification techniques were employed to isolate chemotaxis signaling protein for crystallization. Additional experience was gained in expression vector systems, a minicell expression system for protein identification, and gel retardation assays to examine specific DNA-protein interactions. Experience with DNA footprinting techniques was also obtained.
07/2000 - 08/2006 Fellowship Research: Molecular biology of cardiac gene expression. Specifically, design of an in vivo model using rats to investigate regulatory sequences affecting alpha-myosin heavy chain gene expression. Co-investigator of multi-institutional study: A Phase IV Study of the Safety of Palivizumab (Synagis) for Prophylaxis of Respiratory Syncytial Virus in Children with Congenital Heart Disease.


BIBLIOGRAPHY
Refereed Journal Publications/Original Papers
1. Noel, K.D., Diebold, R.J., Cava J.R. and B.A. Brink. Rhizobial purine and pyrimidine auxotrophs: Nutrient supplementation, genetic analysis, and the symbiotic requirement for de novo purine biosynthesis. Arch. Microbiol. 149:499-506. 1988
2. Cava, J.R., Elias, P.M., Turowski D.A. and K.D. Noel. Rhizobium leguminosarum CFN42 genetic regions encoding lipopolysaccharide structures essential for complete nodule development of bean. J. Bacteriol. 171:8-15. 1989
3. Cava, J.R., Tao H. and K.D. Noel. Mapping of complementation groups within a Rhizobium leguminosarum CFN42 chromosomal region required for lipopolysaccharide synthesis. Mol. Gen. Genet. 221:125-128. 1990
4. Zeller, W.P., Goto, M., Parker, J., Cava, J.R., Gottschalk, M.E., Filkins J.P. and C. Hofmann. 1994. Glucose transporters (GLUT1,2,&4) in fat, muscle and liver in a rat model of endotoxic shock. Biochem. Biophys. Res. Comm. 198:923-927. 1994
5. Allen, B.S., El-Zein, C., Cuneo, B., Cava, J.R., Barth, M.J. and M.N. Ilbawi. Pericardial tissue valves and gore-tex conduits as an alternative for right ventricular outflow tract replacement in children. Soc. of Thorac. Surgeons. 74: 771-777. 2002
6. Ghanayem NS, Hoffman GM, Mussatto KA, Cava JR, Frommelt PC, et al. Home surveillance program prevents interstage mortality following the Norwood procedure. J Thorac Cardiovasc Surg 126(5): 1367-77. 2003
7. Jaquiss RD, Ghanayem NS, Hoffman GM, Fedderly RT, Cava JR, Mussatto KA, Tweddell JS. Early cavopulmonary anastomosis in very young infants after the Norwood procedure: impact on oxygenation, resource utilization, and mortality. J Thorac Cardiovasc Surg 127(4): 982-989. 2004
8. Stuth EA, Stucke AG, Cava JR, Hoffman GM, Berens RJ. Droperidol for perioperative sedation causes a transient prolongation of the QTc time in children under volatile anesthesia. Pediatric Anesthesia.14(10):831-7. 2004
9. Cava JR, Bevandic SM, Steltzer MM, Tweddell JS. A medical strategy to reduce persistent chest tube drainage after the Fontan operation. Am J Cardiol 96(1):130-133. 2005.
10. Berens RJ, Stuth EA, Robertson FA, Jaquiss RD, Hoffman GM, Troshynski TJ, Staudt SR, Cava JR, Tweddell JS, Bert Litwin S. Near infrared spectroscopy monitoring during pediatric aortic coarctation repair. Pediatric Anesthesia 16(7): 777-781. 2006.
11. Zangwill, SD, Brown MD, Bryke CR, Cava JR, Segura AD. Marfan syndrome type II: there is more to Marfan syndrome than fibrillin 1. Congenital Heart Disease. 1(5):229-32. 2006
12. Jaquiss RD, Siehr SL, Ghanayem NS, Hoffman GM, Fedderly RT, Cava JR, Mussatto, KA, Tweddell JS. Early cavopulmonary anastomosis after Norwood procedure results in excellent Fontan outcome. Ann Thorac Surg 82(4): 1260-1266. 2006.
13. Ghanayem, NS, Jaquiss RD, Cava JR, Frommelt PC, Mussatto KA, Hoffman GM, Tweddell JS. Right ventricle-to-pulmonary artery conduit versus Blalock-Taussig shunt: a hemodynamic comparison. Ann Thorac Surg 82(5): 1603-10. 2006.
14. Sachdeva R, Fiser RT, Morrow WR, Cava JR, Ghanayem NS, Jaquiss RD. Ruptured tricuspid valve papillary muscle: a treatable cause of neonatal cyanosis. Ann Thorac Surg. 83(2):680-682, 2007.
15. Johnson, B.A., Hoffman, G.M., Tweddell, J.S., Cava, J.R., Basir, B., Mitchell, M.E., Scanlon, M.C., Mussatto, K.A., and N.S. Ghanayem. Near infrared spectroscopy in neonates before palliation of hypoplastic left heart syndrome. Soc. of Thorac. Surgeons. 87: 571-9, 2009.
16. Kutty S., Cava J., Frommelt MA. Idiopathic infantile arterial calcification: A case report of prenatal and postnatal echocardiographic diagnosis. Echocardiography 26 (7): 862-864, 2009
17. Ghanayem N., Mussatto K., Hoffman G., Frommelt M., Cava J., Mitchell M., Tweddell J. Perioperative monitoring in high-risk infants after stage I palliation of univentricular congenital heart disease. The Journal of Thoracic and Cardiovascular Surgery 140 (4): 857-863, 2010.
18. Jr. LaDisa JF, Dholakia RJ, Figueroa CA, Vignon-Clementel IE, Chan FP, Samyn MM, Cava JR, Taylor CA, Feinstein JA. Computational Simulations Demonstrate Altered Wall Shear Stress in Aortic Coarctation Patients Treated by Resection with End-to-end Anastomosis. Congenital Heart Disease 2011;6:432-443.
19. Beroukhim RS, Prakash A, Valsangiacomo Buechel ER, Cava JR, Dorfman AL, Festa P, Hlavacek AM, Johnson TR, Keller MS, Krishnamurthy R, Misra N, Moniotte S, Parks WJ, Powell AJ, Soriano BD, Srichai MB, Yoo S, Zhou J, Geva T. Characterization of Cardiac Tumors in Children by Cardiovascular Magnetic Resonance Imaging: A Multicenter Experience. J Am Coll Cardiol 2011;58:1044-1054.
20. Bajaj A, Eyke P, Zaleski C, Cava J, McPherson E. Mild Tessier No. 7 cleft with PHACE syndrome: the case for pulmonary vascular steal. Am J Med Genet A 2011 Sep; 115A(9):2298-301.
21. Ginde S, Cava JR, Southern JF, Saudek DE. Delayed contrast-enhanced magnetic resonance imaging in the evaluation of Takayasu arteritis. J Am Coll Cardiol. 2012 Mar 20;59(12):e23.
22. Ginde S, Earing MG, Bartz PJ, Cava JR, Tweddell JS. Late complications after Takeuchi repair of anomalous left coronary artery from the pulmonary artery: case series and review of literature. Pediatr Cardiol. 2012 Oct;33(7):1115-23.
23. Wendell DC, Samyn MM, Cava JR, Ellwein LM, Krolikowski MM, Gandy KL, Pelech AN, Shadden SC, LaDisa JF Jr. Including aortic valve morphology in computational fluid dynamics simulations: initial findings and application to aortic coarctation. Med Eng Phys. 2013 Jun;35(6):723-35. PMCID: PMC3577975
24. Chaves AH, Cava JR, Simpson P, Hoffman GM, Samyn MM. Infant cardiac magnetic resonance imaging using oscillatory ventilation: safe and effective. Pediatr Cardiol. 2013 Jun;34(5):1201-5.
25. Samyn MM, Kwon EN, Gorentz JS, Yan K, Danduran MJ, Cava JR, Simpson PM, Frommelt PC, Tweddell JS. Restrictive versus nonrestrictive physiology following repair of tetralogy of Fallot: is there a difference? J Am Soc Echocardiogr. 2013 Jul;26(7):746-55.
26. Scott J, Stuth EAE, Stucke AG, Cava JR, Berens RJ. Droperidol transiently prolongs the QT interval in children undergoing single ventricle palliation. Pediatr Cardiol. 2015 Jan;36(1):196-204.
27. Sachdeva S, Jacobsen RM, Woods RK, Mitchell ME, Cava JR, Ghanayem NS, Frommelt PC, Bartz PJ, Tweddell JS. Anatomic Repair of Congenitally Corrected Transposition of the Great Arteries: Single-Center Intermediate-Term Experience. Pediatr Cardiol. 2017 Dec;38(8):1696-1702.
28. Wendell DC, Samyn MM, Cava JR, Krolikowski MM, LaDisa JF Jr. The Impact of Cardiac Motion on Aortic Valve Flow Used in Computational Simulations of the Thoracic Aorta. J Biomech Eng. 2016 09 01;138(9). PMCID: PMC4967883
29. Scott JP, Stuth EA, Stucke AG, Cava JR, Berens RJ. Droperidol transiently prolongs the QT interval in children undergoing single ventricle palliation. Pediatr Cardiol. 2015 Jan;36(1):196-204.
 
Books, Chapters, and Reviews
1. Cava JR, Danduran MJ, Fedderly RT and Sayger PL. Exercise recommendations and risk factors for sudden cardiac death. Pediatric Clinics of North America. 51(5), 1401-1420. 2004.
2. Ghanayem NS, Cava JR, Jaquiss RDB and Tweddell JS. Home monitoring of infants after stage one palliation for hypoplastic left heart syndrome. Seminars in Thorac. and Cardiovasc. Surg. 7, 32-38. 2004.
3. Cava JR, and Sayger PL. Chest pain in children and adolescents. Pediatric Clinics of North America 51(6), 1553-1568. 2004.
 
Abstracts
1. Noel, K.D., K.A. VandenBosch, B.C. Kulpaca, J.R. Cava, R.J. Diebold and E.H. Newcomb. Infection mutants of Rhizobium phaseoli. In: Nitrogen Fixation Research Progress. (Evans, Bottomley and Newton eds.). Nijhoff. 1985
2. Noel, K.D., P.M. Pachori, B.C. Kulpaca, K.A. VandenBosch, B.A. Brink and J. R. Cava. Rhizobium mutants defective in lipopolysaccharide and infection. In Molecular Genetics of Plant Microbe Interactions. (D.P.S. Verma and N. Brisson eds.). Nijhoff. 1987
3. Noel, K.D., R.J. Diebold, J.R. Cava and B.A. Brink. Rhizobial de novo purine synthesis:genetic analysis and the requirement for nodule development. p. 660. In: H. Bothe, F.J. de Bruijn and W.E. Newton (eds.) Nitrogen Fixation: Hundred Years After. Gustav Fischer. Stuttgart. 1988
4. Cava, J.R., P.M. Pachori, D.A. Turowski and K.D. Noel. Rhizobial lipopolysaccharide mutants: symbiotic and genetic characterization. p. 472. In: H. Bothe, F.J. de Bruijn and W.E. Newton (eds.) Nitrogen Fixation: Hundred Years After. Gustav Fischer. Stuttgartt 1988
5. Berger, S., J.R. Cava, A.N. Pelech, P.C. Frommelt, G. Hoffman, R. D. Jaquiss and J.S.Tweddell. ECMO and transcatheter left heart decompression in an infant with acute,severe left heart failure. Third World Congress on Pediatric Cardiology. Toronto, Ontario,Canada. 2001
6. Berger, S., J.A. Biller, A.N. Pelech, J.R. Cava, M. Recto, T. Lamorgese, D. Daniels, R.D. Jaquiss, and G. Haasler. Stroke In A Young Man with Cystic Fibrosis after Lung Transplantation. Third World Congress on Pediatric Cardiology. Toronto, Ontario,Canada. 2001
7. Cava, J.R., R.T. Fedderly, S. M. Bevandic, M. Steltzer, P. J. Phelan, K. N. Hor, J.S. Tweddell and S. B. Litwin. A medical strategy to address persistent chest tube drainage after the Fontan operation. ACC 02, Atlanta, Georgia, 2002.
8. Stuth E, Hoffman GM, Berens R, Cava JR, Ghanayem N, Mussatto K et al. A randomized, double-blind study of regional vs. intravenous analgesia to promote early endotracheal extubation in children undergoing single ventricle palliation. In progress.
9. Jaquiss RD, Ghanayem NS, Hoffman GM, Fedderly RT, Cava JR et al. Early cavopulmonary anastomosis is safe after Norwood Procedure. 29th Annual Meeting of the Western Thoracic Surgical Association. La Costa Resort, Carlsbad, CA. June 2003.
10. Stuth E, Stucke A, Cava JR, Hoffman G, Behrens R. Droperidol for perioperative sedation causes a transient prolongation of the QTc time in children during cardiac surgery. ASA 2002 Annual Meeting.
11. Ghanayem NS, Cava JR, Troshynski TJ, Jaquiss RD, and GM Hoffman. Somatic blood flow by NIRS monitoring predicts renal insufficiency following neonatal cardiac surgery.AHA 2004 Annual Meeting. New Orleans, LA.
12. Stuth EAE, Berens RJ, Hoffman GM, Robertson F, Staudt S, Troshynski, T, Ghanayem N,Cava JR, Stucke A, Colpaert K, Tweddell JS, and RD Jaquiss. Use of NIRS oximetry in Glenn and Fontan procedures. ASA 2004 Annual Meeting.
13. Hoffman GM, Ghanayem N, Mussatto KA, Cava JR, Musa N, Flynn-Galganski M, Pelech AN, Jaquiss RD, and JS Tweddell. Perioperative somatic near-infrared spectroscopy predicts postoperative renal function following neonatal cardiac surgery. American Heart Association, Dallas, TX 2005.
14. Jaquiss RDB, Siehr BS, Ghanayem NS, Hoffman GM, Fedderly RT, Cava JR, Mussatto KA, and JS Tweddell. Early cavopulmonary anastomosis after Norwood procedure results in excellent Fontan outcome. Midwest Pediatric Cardiology Society Meeting, Iowa City,IA 2005.
15. Tweddell JS, Hoffman GM, Ghanayem NS, Musa N, and JR Cava. Strategies to improve systemic oxygen delivery following stage 1 palliation for hypoplastic left heart syndrome. World Congress of Pediatric Cardiology, Buenos Aires, Argentina, 2005.
16. Wehrheim, K, Krolikowski, M, Mussatto, K, Danduran, M, Cava, J, and M Samyn. Retrospective review of the management of patients with aortic valve regurgitation. Midwest Pediatric Cardiology Conference. St. Louis, MO 2007.
17. Johnson, BA, Tweddell, JS, Cava, JR, Hoffman, GM, Basir, M, Mussatto, KA, Mitchell, ME, Scanlon, MC and NS Ghanayem. Clinical utility of near infrared spectroscopy in neonates prior to stage I palliation of hypoplastic left heart syndrome. STS. Ft. Lauderdale, FL 2008.
18. BA Johnson, GM Hoffman, JS Tweddell, JR Cava, M Basir, ME Mitchell, M Scanlon, KA Mussatto, and NS Ghanayem. Clinical utility of near infrared spectroscopy in neonates prior to stage I palliation of hypoplastic left heart syndrome. STS. Ft. Lauderdale, FL 2008.
19. Samyn MM, Saudek DE, Dasgupta M, Schnell AK, Krolikowski M, Simpson PM, Cava JR, Frommelt PC. Are echocardiographic and cardiac magnetic resonance assessments reliable and reproducible in patients with a systemic right ventricle? American Society of Echocardiography. Washington DC, 2009.
20. Kwon EN, Yan K, Kutty S, Gorentz J, Danduran MJ, Simpson PM, Cava JR, Frommelt PC, Samyn MM. Global and regional right ventricular function and exercise capacity in postoperative tetralogy of fallot: An echocardiographic and cardiac magnetic resonance imaging study. American Society of Echocardiography. Washington DC, 2009.
21. Dholakia R, Wendell D, Cava J, Krolikowski M, Samyn M, LaDisa J. A comparative study of hemodynamics in coarctation patients treated with Dacron patch aortoplasty and normal subjects. BIEN Graduate Symposium - Marquette University, Milwaukee, WI, 2009.
22. Wendell D, Cava J, Samyn M, LaDisa J. Influence of aortic valve morphology on arch hemodynamics and successful aortic coarctation repair. Biomedical Engineering Society, Pittsburgh, PA, 2009.
23. Chaves AH, Cava JR, Simpson P, Hoffman G, Samyn MM. Infant cardiac MRI using oscillatory ventilation: Safe and effective. Society of Cardiovascualar Magnetic Resonance. Orlando, FL 2012
24. James S. Tweddell, Roni M. Jacobsen, Ronald K. Woods, Michael E. Mitchell, Joseph R. Cava, Nancy S. Ghanayem. Peter C. Frommelt, Peter J. Bartz. Children's Hospital of Wisconsin: Anatomic Repair of Congenitally Corrected Transposition of the Great Arteries, Chicago, IL October 2015
25. Shagun Sachdeva, Salil Ginde, Benjamin H Goot, Joseph Cava, Peter C Frommelt. Echocardiographic and Cardiac MRI Deformation Analysis in Patients with Single Left Ventricle vs Right Ventricle Post Fontan Surgery. American Society of Echocardiography 2018
26. Adam Gordon, Benjamin H Goot, Ann Punnoose, Ke Yan, Joseph Cava, Mary Krolikowski, Margaret M Samyn. Evaluation of Myocardial T1 Mapping and Extracellular Volume (ECV) After Pediatric Heart Transplantation. Midwest Society Meeting, St. Louis MO, 9/8/17
 

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