Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

John A. Pulikkan PhD

Assistant Professor

Institution: Medical College of Wisconsin
Department: Cell Biology, Neurobiology and Anatomy
Program: Administration


Publications

  • CBFβ-SMMHC Inhibition Triggers Apoptosis by Disrupting MYC Chromatin Dynamics in Acute Myeloid Leukemia. (Pulikkan JA, Hegde M, Ahmad HM, Belaghzal H, Illendula A, Yu J, O'Hagan K, Ou J, Muller-Tidow C, Wolfe SA, Zhu LJ, Dekker J, Bushweller JH, Castilla LH) Cell 2018 06 28;174(1):172-186.e21 PMID: 29958106 PMCID: PMC6211564 06/30/2018       3 Citations
  • Preleukemia and Leukemia-Initiating Cell Activity in inv(16) Acute Myeloid Leukemia. (Pulikkan JA, Castilla LH) Front Oncol 2018;8:129 PMID: 29755956 PMCID: PMC5932169 05/15/2018    
  • C/EBPα deregulation as a paradigm for leukemogenesis. (Pulikkan JA, Tenen DG, Behre G) Leukemia 2017 11;31(11):2279-2285 PMID: 28720765 07/20/2017       11 Citations
  • Chemical biology. A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice. (Illendula A, Pulikkan JA, Zong H, Grembecka J, Xue L, Sen S, Zhou Y, Boulton A, Kuntimaddi A, Gao Y, Rajewski RA, Guzman ML, Castilla LH, Bushweller JH) Science 2015 Feb 13;347(6223):779-84 PMID: 25678665 PMCID: PMC4423805 02/14/2015       43 Citations
  • Thrombopoietin/MPL participates in initiating and maintaining RUNX1-ETO acute myeloid leukemia via PI3K/AKT signaling. (Pulikkan JA, Madera D, Xue L, Bradley P, Landrette SF, Kuo YH, Abbas S, Zhu LJ, Valk P, Castilla LH) Blood 2012 Jul 26;120(4):868-79 PMID: 22613795 PMCID: PMC3412349 05/23/2012       32 Citations
  • C/EBPα regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations. (Pulikkan JA, Peramangalam PS, Dengler V, Ho PA, Preudhomme C, Meshinchi S, Christopeit M, Nibourel O, Müller-Tidow C, Bohlander SK, Tenen DG, Behre G) Blood 2010 Dec 16;116(25):5638-49 PMID: 20889924 PMCID: PMC3031410 10/05/2010       92 Citations
  • Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AML. (Pulikkan JA, Dengler V, Peer Zada AA, Kawasaki A, Geletu M, Pasalic Z, Bohlander SK, Ryo A, Tenen DG, Behre G) Leukemia 2010 May;24(5):914-23 PMID: 20376080 PMCID: PMC2923485 04/09/2010    
  • Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia. (Pulikkan JA, Dengler V, Peramangalam PS, Peer Zada AA, Müller-Tidow C, Bohlander SK, Tenen DG, Behre G) Blood 2010 Mar 04;115(9):1768-78 PMID: 20029046 PMCID: PMC2832809 12/24/2009       194 Citations
  • Last update: 04/03/2019
    jenkins-FCD Prod-336 69ef4a6b262d135130251597d5d39873903802b5