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Kunal Gupta MD, PhD

Kunal Gupta MD, PhD profile photo picture

Assistant Professor

Institution: Medical College of Wisconsin
Department: Neurosurgery
Program: Adult

Member of the Wisconsin Institute of NeuroScience (WINS)

View Curriculum Vitae

Research Areas of Interest

  • Epilepsy
  • Epilepsy, Temporal Lobe
  • Neurosciences

    • Publications (25)

  • Canonical Wnt activator Chir99021 prevents epileptogenesis in the intrahippocampal kainate mouse model of temporal lobe epilepsy (Mardones MD, Rostam KD, Nickerson MC, Gupta K) Experimental Neurology June 2024;376 SCOPUS ID: 2-s2.0-85188911182 06/01/2024    
  • Bilateral Deep Brain Stimulation of the Ventral Intermediate Nucleus of the Thalamus Improves Objective Acoustic Measures of Essential Vocal Tremor. (Patel R, Burroughs L, Higgins A, Zauber SE, Isbaine F, Schneider D, Hohman R, Gupta K) Neurosurgery 2024 Apr 22 PMID: 38787392 05/24/2024    
  • Insights into epileptogenesis from post-traumatic epilepsy. (Pease M, Gupta K, Moshé SL, Correa DJ, Galanopoulou AS, Okonkwo DO, Gonzalez-Martinez J, Shutter L, Diaz-Arrastia R, Castellano JF) Nat Rev Neurol 2024 May;20(5):298-312 PMID: 38570704 SCOPUS ID: 2-s2.0-85189313072 04/04/2024       4 Citations
  • Canonical Wnt activator Chir99021 prevents epileptogenesis in the intrahippocampal kainate mouse model of temporal lobe epilepsy. (Mardones MD, Rostam KD, Nickerson MC, Gupta K) Exp Neurol 2024 Jun;376:114767 PMID: 38522659 PMCID: PMC11058011 SCOPUS ID: 2-s2.0-85188911182 03/25/2024    
  • Transcriptome Profiling of the Hippocampal Seizure Network Implicates a Role for Wnt Signaling during Epileptogenesis in a Mouse Model of Temporal Lobe Epilepsy. (Mardones MD, Gupta K) Int J Mol Sci 2022 Oct 10;23(19) PMID: 36233336 PMCID: PMC9569502 SCOPUS ID: 2-s2.0-85139980008 10/15/2022       6 Citations
  • Globus Pallidus Interna and Ventral Intermediate Nucleus of the Thalamus Deep Brain Stimulation for Adductor Laryngeal Dystonia: a Case Report of Blinded Analyses of Objective Voice Outcomes in 2 Patients. (Patel RR, Zauber SE, Yadav AP, Witt TC, Halum S, Gupta K) Neurosurgery 2022 Apr 01;90(4):457-463 PMID: 35138294 SCOPUS ID: 2-s2.0-85126830952 02/10/2022       1 Citation
  • Programming Parameters and Techniques in Trigeminal Ganglion Stimulation for Intractable Facial Pain. (Gupta K, Texakalidis P, Boulis NM) Neuromodulation 2021 Aug;24(6):1100-1106 PMID: 33145871 SCOPUS ID: 2-s2.0-85096685914 11/05/2020       4 Citations
  • Stereotactic MRI-guided laser interstitial thermal therapy for extratemporal lobe epilepsy. (Gupta K, Cabaniss B, Kheder A, Gedela S, Koch P, Hewitt KC, Alwaki A, Rich C, Ramesha S, Hu R, Drane DL, Gross RE, Willie JT) Epilepsia 2020 Aug;61(8):1723-1734 PMID: 32777090 PMCID: PMC8019400 SCOPUS ID: 2-s2.0-85089201160 08/11/2020       36 Citations
  • Novel Use of Stimulating Fence-Post Technique for Functional Mapping of Subcortical White Matter During Tumor Resection: A Technical Case Series. (Han SJ, Teton Z, Gupta K, Kawamoto A, Raslan AM) Oper Neurosurg (Hagerstown) 2020 Sep 01;19(3):264-270 PMID: 32133508 SCOPUS ID: 2-s2.0-85089608106 03/07/2020       6 Citations
  • Neuronal network remodeling and Wnt pathway dysregulation in the intra-hippocampal kainate mouse model of temporal lobe epilepsy. (Gupta K, Schnell E) PLoS One 2019;14(10):e0215789 PMID: 31596871 PMCID: PMC6785072 SCOPUS ID: 2-s2.0-85073053846 10/10/2019       11 Citations
  • Delivery Methods for Treatment of Genetic Disorders (Gupta K, Selden NR) Nervous System Drug Delivery: Principles and Practice 25 June 2019:447-461 SCOPUS ID: 2-s2.0-85083811294 06/25/2019    
  • Lumbar laminotomy for the intrathecal administration of nusinersen for spinal muscular atrophy: technical note and outcomes. (Ko D, Blatt D, Karam C, Gupta K, Raslan AM) J Neurosurg Spine 2019 Aug 01;31(2):217-221 PMID: 31003222 SCOPUS ID: 2-s2.0-85073652817 04/20/2019       14 Citations
  • Cortical dysplasia and extratemporal resections in epilepsy (Gupta K, Selden NR) Functional Neurosurgery and Neuromodulation 1 January 2018:129-136 SCOPUS ID: 2-s2.0-85092587662 01/01/2018    
  • Elucidating Pro-Inflammatory Cytokine Responses after Traumatic Brain Injury in a Human Stem Cell Model. (Thelin EP, Hall CE, Gupta K, Carpenter KLH, Chandran S, Hutchinson PJ, Patani R, Helmy A) J Neurotrauma 2018 Jan 15;35(2):341-352 PMID: 28978285 PMCID: PMC5784793 SCOPUS ID: 2-s2.0-85041057115 10/06/2017       39 Citations
  • Intraoperative Computed Tomography and Nexframe-Guided Placement of Bilateral Hippocampal-Based Responsive Neurostimulation: Technical Note. (Gupta K, Raskin JS, Raslan AM) World Neurosurg 2017 May;101:161-169 PMID: 28185967 SCOPUS ID: 2-s2.0-85015657681 02/12/2017       7 Citations
  • Neurosurgical management in lateral meningocele syndrome: case report. (Brown EC, Gupta K, Sayama C) J Neurosurg Pediatr 2017 Feb;19(2):232-238 PMID: 27911244 SCOPUS ID: 2-s2.0-85013040208 12/03/2016       9 Citations
  • Atypical facial pain in multiple sclerosis caused by spinal cord seizures: a case report and review of the literature. (Gupta K, Burchiel KJ) J Med Case Rep 2016 Apr 20;10:101 PMID: 27095098 PMCID: PMC4837532 SCOPUS ID: 2-s2.0-84966286503 04/21/2016       5 Citations
  • Classification of middle fossa floor dehiscence syndromes. (Gupta K, Sabry HA, Dogan A, Coppa ND, McMenomey S, Delashaw JB, Raslan AM) J Neurosurg 2015 Mar;122(3):557-63 PMID: 25554855 SCOPUS ID: 2-s2.0-84927973270 01/03/2015       8 Citations
  • NMDA receptor-dependent glutamate excitotoxicity in human embryonic stem cell-derived neurons. (Gupta K, Hardingham GE, Chandran S) Neurosci Lett 2013 May 24;543:95-100 PMID: 23518152 PMCID: PMC3725411 SCOPUS ID: 2-s2.0-84877131133 03/23/2013       58 Citations
  • Human stem cell-derived astrocytes and their application to studying Nrf2-mediated neuroprotective pathways and therapeutics in neurodegeneration. (Gupta K, Chandran S, Hardingham GE) Br J Clin Pharmacol 2013 Apr;75(4):907-18 PMID: 23126226 PMCID: PMC3612708 SCOPUS ID: 2-s2.0-84875060374 11/07/2012       28 Citations
  • Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms. (Gupta K, Patani R, Baxter P, Serio A, Story D, Tsujita T, Hayes JD, Pedersen RA, Hardingham GE, Chandran S) Cell Death Differ 2012 May;19(5):779-87 PMID: 22095276 PMCID: PMC3321621 SCOPUS ID: 2-s2.0-84859617138 11/19/2011       72 Citations
  • Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning. (Bell KF, Al-Mubarak B, Fowler JH, Baxter PS, Gupta K, Tsujita T, Chowdhry S, Patani R, Chandran S, Horsburgh K, Hayes JD, Hardingham GE) Proc Natl Acad Sci U S A 2011 Jan 04;108(1):E1-2; author reply E3-4 PMID: 21177433 PMCID: PMC3017195 SCOPUS ID: 2-s2.0-78651099584 12/24/2010       115 Citations
  • Doctors: fighting fit or couch potatoes? (Gupta K, Fan L) Br J Sports Med 2009 Feb;43(2):153-4 PMID: 19050002 SCOPUS ID: 2-s2.0-61449199428 12/04/2008       19 Citations
  • Multifunctional roles for serum protein fetuin-a in inhibition of human vascular smooth muscle cell calcification. (Reynolds JL, Skepper JN, McNair R, Kasama T, Gupta K, Weissberg PL, Jahnen-Dechent W, Shanahan CM) J Am Soc Nephrol 2005 Oct;16(10):2920-30 PMID: 16093453 SCOPUS ID: 2-s2.0-33645269267 08/12/2005       308 Citations
  • Tumor suppressor activity and epigenetic inactivation of hepatocyte growth factor activator inhibitor type 2/SPINT2 in papillary and clear cell renal cell carcinoma. (Morris MR, Gentle D, Abdulrahman M, Maina EN, Gupta K, Banks RE, Wiesener MS, Kishida T, Yao M, Teh B, Latif F, Maher ER) Cancer Res 2005 Jun 01;65(11):4598-606 PMID: 15930277 SCOPUS ID: 2-s2.0-21144447438 06/03/2005       106 Citations
    • Last update: 06/16/2024