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Thomas Mcfall PhD
Assistant Professor
Institution:
Medical College of Wisconsin
Department:
Biochemistry
Program:
Program Development
Member of the
Cancer Center
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View Curriculum Vitae
Publications (12)
Identification of RAS mutant biomarkers for EGFR inhibitor sensitivity using a systems biochemical approach.
(McFall T, Stites EC)
Cell Rep
2021 Dec 14;37(11):110096 PMID: 34910921 PMCID: PMC8867612 SCOPUS ID: 2-s2.0-85121146579 12/16/2021
6 Citations
KRAS-Mutated, Estrogen Receptor-Positive Low-Grade Serous Ovarian Cancer: Unraveling an Exceptional Response Mystery.
(Kato S, McFall T, Takahashi K, Bamel K, Ikeda S, Eskander RN, Plaxe S, Parker B, Stites E, Kurzrock R)
Oncologist
2021 Apr;26(4):e530-e536 PMID: 33528846 PMCID: PMC8018312 SCOPUS ID: 2-s2.0-85101866994 02/03/2021
6 Citations
Discernment between candidate mechanisms for KRAS G13D colorectal cancer sensitivity to EGFR inhibitors.
(McFall T, Schomburg NK, Rossman KL, Stites EC)
Cell Commun Signal
2020 Nov 05;18(1):179 PMID: 33153459 PMCID: PMC7643456 SCOPUS ID: 2-s2.0-85095115047 11/07/2020
6 Citations
A mechanism for the response of KRAS
G13D
expressing colorectal cancers to EGFR inhibitors.
(McFall T, Stites EC)
Mol Cell Oncol
2020;7(2):1701914 PMID: 32158916 PMCID: PMC7051129 SCOPUS ID: 2-s2.0-85078303987 03/12/2020
6 Citations
A systems mechanism for KRAS mutant allele-specific responses to targeted therapy.
(McFall T, Diedrich JK, Mengistu M, Littlechild SL, Paskvan KV, Sisk-Hackworth L, Moresco JJ, Shaw AS, Stites EC)
Sci Signal
2019 Sep 24;12(600) PMID: 31551296 PMCID: PMC6864030 SCOPUS ID: 2-s2.0-85072619385 09/26/2019
36 Citations
Chronic p27
Kip1
Induction by Dexamethasone Causes Senescence Phenotype and Permanent Cell Cycle Blockade in Lung Adenocarcinoma Cells Over-expressing Glucocorticoid Receptor.
(Patki M, McFall T, Rosati R, Huang Y, Malysa A, Polin L, Fielder A, Wilson MR, Lonardo F, Back J, Li J, Matherly LH, Bepler G, Ratnam M)
Sci Rep
2018 Oct 30;8(1):16006 PMID: 30375484 PMCID: PMC6207728 SCOPUS ID: 2-s2.0-85055615805 10/31/2018
8 Citations
Strategy for Tumor-Selective Disruption of Androgen Receptor Function in the Spectrum of Prostate Cancer.
(Rosati R, Polin L, Ducker C, Li J, Bao X, Selvakumar D, Kim S, Xhabija B, Larsen M, McFall T, Huang Y, Kidder BL, Fribley A, Saxton J, Kakuta H, Shaw P, Ratnam M)
Clin Cancer Res
2018 Dec 15;24(24):6509-6522 PMID: 30185422 PMCID: PMC6295231 SCOPUS ID: 2-s2.0-85058440559 09/07/2018
14 Citations
Progesterone receptor A promotes invasiveness and metastasis of luminal breast cancer by suppressing regulation of critical microRNAs by estrogen.
(McFall T, McKnight B, Rosati R, Kim S, Huang Y, Viola-Villegas N, Ratnam M)
J Biol Chem
2018 Jan 26;293(4):1163-1177 PMID: 29162724 PMCID: PMC5787796 SCOPUS ID: 2-s2.0-85041241242 11/23/2017
31 Citations
The Amino-terminal Domain of the Androgen Receptor Co-opts Extracellular Signal-regulated Kinase (ERK) Docking Sites in ELK1 Protein to Induce Sustained Gene Activation That Supports Prostate Cancer Cell Growth.
(Rosati R, Patki M, Chari V, Dakshnamurthy S, McFall T, Saxton J, Kidder BL, Shaw PE, Ratnam M)
J Biol Chem
2016 Dec 09;291(50):25983-25998 PMID: 27793987 PMCID: PMC5207070 SCOPUS ID: 2-s2.0-85002706288 10/30/2016
13 Citations
Hybrid Enzalutamide Derivatives with Histone Deacetylase Inhibitor Activity Decrease Heat Shock Protein 90 and Androgen Receptor Levels and Inhibit Viability in Enzalutamide-Resistant C4-2 Prostate Cancer Cells.
(Rosati R, Chen B, Patki M, McFall T, Ou S, Heath E, Ratnam M, Qin Z)
Mol Pharmacol
2016 Sep;90(3):225-37 PMID: 27382012 PMCID: PMC4998664 SCOPUS ID: 2-s2.0-84984848137 07/07/2016
18 Citations
Role of the short isoform of the progesterone receptor in breast cancer cell invasiveness at estrogen and progesterone levels in the pre- and post-menopausal ranges.
(McFall T, Patki M, Rosati R, Ratnam M)
Oncotarget
2015 Oct 20;6(32):33146-64 PMID: 26356672 PMCID: PMC4741755 SCOPUS ID: 2-s2.0-84946031365 09/12/2015
13 Citations
Glucocorticoid receptor status is a principal determinant of variability in the sensitivity of non-small-cell lung cancer cells to pemetrexed.
(Patki M, Gadgeel S, Huang Y, McFall T, Shields AF, Matherly LH, Bepler G, Ratnam M)
J Thorac Oncol
2014 Apr;9(4):519-26 PMID: 24736075 PMCID: PMC4075060 SCOPUS ID: 2-s2.0-84922479677 04/17/2014
26 Citations
Last update: 03/01/2024