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Breastfeeding and genetic factors in the etiology of inflammatory bowel disease in children. World J Gastroenterol 2009 Jan 21;15(3):270-9

Date

01/14/2009

Pubmed ID

19140226

Pubmed Central ID

PMC2653323

DOI

10.3748/wjg.15.270

Scopus ID

2-s2.0-59249106391   36 Citations

Abstract

Inflammatory bowel disease is a chronic, debilitating disorder of the gastrointestinal tract. The etiology of inflammatory bowel disease has not been elucidated, but is thought to be multifactorial with both environ-mental and genetic influences. A large body of research has been conducted to elucidate the etiology of inflammatory bowel disease. This article reviews this literature, emphasizing the studies of breastfeeding and the studies of genetic factors, particularly NOD2 polymorphisms.

Author List

Mikhailov TA, Furner SE

Author

Theresa A. Mikhailov MD, PhD Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Breast Feeding
Contraceptives, Oral
Genetic Predisposition to Disease
Humans
Inflammatory Bowel Diseases
Meta-Analysis as Topic
Nod2 Signaling Adaptor Protein
Polymorphism, Genetic
jenkins-FCD Prod-444 eb4ebd1a08581aba961d3befd3b851a3c3ec6b46