Breastfeeding and genetic factors in the etiology of inflammatory bowel disease in children. World J Gastroenterol 2009 Jan 21;15(3):270-9
Date
01/14/2009Pubmed ID
19140226Pubmed Central ID
PMC2653323DOI
10.3748/wjg.15.270Scopus ID
2-s2.0-59249106391 (requires institutional sign-in at Scopus site) 43 CitationsAbstract
Inflammatory bowel disease is a chronic, debilitating disorder of the gastrointestinal tract. The etiology of inflammatory bowel disease has not been elucidated, but is thought to be multifactorial with both environ-mental and genetic influences. A large body of research has been conducted to elucidate the etiology of inflammatory bowel disease. This article reviews this literature, emphasizing the studies of breastfeeding and the studies of genetic factors, particularly NOD2 polymorphisms.
Author List
Mikhailov TA, Furner SEAuthor
Theresa A. Mikhailov MD, PhD Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Breast FeedingContraceptives, Oral
Genetic Predisposition to Disease
Humans
Inflammatory Bowel Diseases
Meta-Analysis as Topic
Nod2 Signaling Adaptor Protein
Polymorphism, Genetic