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Factors associated with SF-12 physical and mental health quality of life scores in adults with stroke. J Stroke Cerebrovasc Dis 2013 May;22(4):309-17 PMID: 22005038

Pubmed ID





BACKGROUND: Studies of poststroke quality of life (QOL) have not consistently identified which factors are most likely to independently influence the physical and mental aspects of QOL. In this study, we sought to identify which sociodemographic, comorbid disease conditions, and disability factors independently influenced the physical and mental aspects of poststroke QOL.

METHODS: We completed a cross-sectional study of 666 US adults with a history of stroke from the 2007 Medical Expenditure Panel Survey (MEPS). We used sequentially built multiple linear regression models to identify sociodemographic, comorbidity, and stroke-related disability factors that independently affected short form-12 (SF-12) physical component summary (PCS) and mental component summary (MCS) scores. STATA software (version 10; StataCorp LP, College Station, TX) was used to perform the analysis to account for the complex survey design of the MEPS.

RESULTS: In fully adjusted models using a nationally representative sample of US adults, being non-Hispanic black (β = 3.58), 45 to 64 years of age (β = -3.48), 65 years of age or older (β = -2.90), married (β = -3.50), middle (β = 2.78) and high income (β = 3.73), or having hypertension (β = -2.25), cardiovascular disease (β = -2.05), arthritis (β = -4.49), depression (β = -2.98), physical limitations (β = -7.60), social limitations (β = -4.12), and a need for assistance with instrumental activities of daily living (β = -4.49) were independently correlated with PCS scores. Being 45 to 64 years of age (β = 3.96), depressed (β = -15.92), or having social limitations (β = -3.62) were independently correlated with MCS scores.

CONCLUSIONS: Sociodemographic, comorbidity, and stroke-related disability factors have differential effect on physical and mental aspects of QOL in poststroke patients.

Author List

Ellis C, Grubaugh AL, Egede LE


Leonard E. Egede MD Center Director, Chief, Professor in the Medicine department at Medical College of Wisconsin


2-s2.0-84877032343   22 Citations

MESH terms used to index this publication - Major topics in bold

Activities of Daily Living
African Americans
Age Factors
Cross-Sectional Studies
Disability Evaluation
Health Status
Linear Models
Mental Health
Middle Aged
Predictive Value of Tests
Quality of Life
Recovery of Function
Risk Factors
Surveys and Questionnaires
United States
jenkins-FCD Prod-353 9ccd8489072cb19f5b9f808bb23ed672c582f41e