Faculty Collaboration Database

Epidemiology, diagnosis, prevention and treatment of catheter-related thrombosis in children and adults. Thromb Res 2017 Sep;157:64-71

Date

07/16/2017

Pubmed ID

28710972

DOI

10.1016/j.thromres.2017.07.002

Scopus ID

2-s2.0-85021923944 (requires institutional sign-in at Scopus site)   57 Citations

Abstract

In this narrative review, the epidemiology, diagnosis, prevention strategies, and management of catheter-related thrombosis are outlined. Central venous catheters have significantly improved the quality of life of patients requiring chemotherapy, parenteral nutrition, and chronic transfusions. Catheter-related thrombosis (CRT) complicates between 1-5% of inserted catheters, with incidence varying between patient population, catheter type, and vein cannulated. Strategies to prevent CRT, including anticoagulation and locking solutions, have largely been ineffective. Using clinical decision tools and D-dimer testing can limit radiographic testing for patients with suspected CRT. Although most patients with CRT are treated with anticoagulation, the most effective type and duration of treatment have not been established for adults or children. Many unanswered questions remain concerning risk stratification, prevention, and management of CRT. National and international collaborative research networks could be harnessed to perform these much needed studies.

Author List

Baumann Kreuziger L, Jaffray J, Carrier M

Author

Lisa M. Baumann Kreuziger MD Associate Professor in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Central Venous Catheters
Child
Child, Preschool
Female
Humans
Male
Quality of Life
Risk Factors
Upper Extremity Deep Vein Thrombosis
Young Adult