Medical College of Wisconsin
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Alternative donor transplants for leukemia. Scientific Advisory Committee of the International Bone Marrow Transplant Registry. Bone Marrow Transplant 1993;11 Suppl 1:66-7 PMID: 8448552

Pubmed ID

8448552

Abstract

We analyzed transplant outcome in more than 2,500 recipients of alternative donor and HLA-identical sibling transplants. These data indicate: (1) results of alternative donor transplants are inferior to HLA-identical sibling transplants; (2) zero HLA-antigen disparate unrelated and one HLA-antigen disparate related donors have comparable results; (3) amongst unrelated donors, zero and one HLA-antigen disparity has comparable results; and (4), amongst related transplants, two HLA-antigen disparate transplants fare worse than one HLA-antigen disparate transplants. These data should be useful in deciding when to use an alternative donor and selecting the best donor.

Author List

Gale RP, Horowitz MM

Author

Mary M. Horowitz MD, MS Center Director, Professor in the Medicine department at Medical College of Wisconsin




Scopus

2-s2.0-0027523646   3 Citations

MESH terms used to index this publication - Major topics in bold

Bone Marrow Transplantation
HLA Antigens
Histocompatibility
Humans
Leukemia
Multivariate Analysis
Tissue Donors
jenkins-FCD Prod-299 9ef562391eceb2b8f95265c767fbba1ce5a52fd6