Faculty Collaboration Database

The interaction between RTX toxins and target cells. Trends Microbiol 1999 Sep;7(9):356-61

Date

09/02/1999

Pubmed ID

10470043

DOI

10.1016/s0966-842x(99)01530-9

Scopus ID

2-s2.0-0033198608 (requires institutional sign-in at Scopus site)   223 Citations

Abstract

RTX toxins are important virulence factors produced by a wide range of Gram-negative bacteria. They fall into two categories: the hemolysins, which affect a variety of cell types, and the leukotoxins, which are cell-type- and species-specific. These toxins offer interesting models for targeting, insertion and translocation of aqueous proteins into lipid membranes.

Author List

Lally ET, Hill RB, Kieba IR, Korostoff J

MESH terms used to index this publication - Major topics in bold

Animals
Apoptosis
Bacterial Toxins
Cell Membrane
Cytotoxins
Exotoxins
Gram-Negative Bacteria
Hemolysin Proteins
Humans
Necrosis