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Objective testing and quality-of-life evaluation in surgical candidates with chronic rhinosinusitis. Am J Rhinol 2003 Nov-Dec;17(6):351-6 PMID: 14750611

Pubmed ID



BACKGROUND: Discordance has been reported between patient symptoms and objective measures of disease in chronic sinusitis, such as radiographic evaluation. The objective of this study was to evaluate the association between presurgical objective studies and presurgical quality of life (QOL). This work was designed as a cross-sectional study of 90 consecutive patients presenting to a tertiary rhinology practice for surgical management of sinonasal disease.

METHODS: QOL assessment was performed using disease-specific instruments (Chronic Sinusitis Survey and Rhinosinusitis Disability Index). Computed tomography (CT) scans were scored according to the Lund-Mackay CT scoring system and endoscopy evaluation was scored by the system proposed by Lund and Kennedy.

RESULTS: Ninety surgical candidates were enrolled and included in the analysis. Correlation between the QOL total scores and subscale scores was excellent (r = 0.39; p = 0.0001) as was the correlation between CT and endoscopy scores (r = 0.59; p = 0.0001). In contrast, correlation between QOL and objective measures was poor. These results were not significantly influenced by subgroup analysis by diagnosis, comorbidity, and other patient factors.

CONCLUSION: Preoperative objective measures of CRS disease show little, if any, correlation with disease-specific QOL measures in surgical candidates. It is likely that CT and endoscopy are measuring a different aspect of CRS disease than the QOL measures. In addition, it is possible that preoperative QOL, either alone or in combination with CT and endoscopy, may prove important in selecting patients most likely to benefit from surgery.

Author List

Smith TL, Rhee JS, Loehrl TA, Burzynski ML, Laud PW, Nattinger AB


Purushottam W. Laud PhD Professor in the Institute for Health and Equity department at Medical College of Wisconsin
Todd A. Loehrl MD Chief, Professor in the Otolaryngology department at Medical College of Wisconsin
Ann B. Nattinger MD, MPH Associate Provost, Professor in the Medicine department at Medical College of Wisconsin
John S. Rhee MD Chair, Professor in the Otolaryngology department at Medical College of Wisconsin


2-s2.0-1642463538   30 Citations

MESH terms used to index this publication - Major topics in bold

Chronic Disease
Middle Aged
Paranasal Sinuses
Quality of Life
Surveys and Questionnaires
Tomography, X-Ray Computed
jenkins-FCD Prod-299 9ef562391eceb2b8f95265c767fbba1ce5a52fd6