Medical College of Wisconsin
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Adaptive optics retinal imaging--clinical opportunities and challenges. Curr Eye Res 2013 Jul;38(7):709-21 PMID: 23621343 PMCID: PMC4031042

Pubmed ID





The array of therapeutic options available to clinicians for treating retinal disease is expanding. With these advances comes the need for better understanding of the etiology of these diseases on a cellular level as well as improved non-invasive tools for identifying the best candidates for given therapies and monitoring the efficacy of those therapies. While spectral domain optical coherence tomography offers a widely available tool for clinicians to assay the living retina, it suffers from poor lateral resolution due to the eye's monochromatic aberrations. Ophthalmic adaptive optics (AO) is a technique to compensate for the eye's aberrations and provide nearly diffraction-limited resolution. The result is the ability to visualize the living retina with cellular resolution. While AO is unquestionably a powerful research tool, many clinicians remain undecided on the clinical potential of AO imaging - putting many at a crossroads with respect to adoption of this technology. This review will briefly summarize the current state of AO retinal imaging, discuss current as well as future clinical applications of AO retinal imaging, and finally provide some discussion of research needs to facilitate more widespread clinical use.

Author List

Carroll J, Kay DB, Scoles D, Dubra A, Lombardo M


Joseph J. Carroll PhD Director, Professor in the Ophthalmology and Visual Sciences department at Medical College of Wisconsin


2-s2.0-84878512871   47 Citations

MESH terms used to index this publication - Major topics in bold

Diagnostic Techniques, Ophthalmological
Optical Imaging
Photoreceptor Cells, Vertebrate
Retinal Diseases
jenkins-FCD Prod-353 9ccd8489072cb19f5b9f808bb23ed672c582f41e