Faculty Collaboration Database

Asymptomatic inflammatory bowel disease presenting with mucocutaneous findings. Pediatrics 2005 Sep;116(3):e439-44

Date

08/16/2005

Pubmed ID

16099852

DOI

10.1542/peds.2004-2281

Scopus ID

2-s2.0-33644631846 (requires institutional sign-in at Scopus site)   70 Citations

Abstract

Although inflammatory bowel disease (IBD) typically presents with gastrointestinal complaints, mucocutaneous lesions are commonly associated and can precede gastrointestinal symptoms, thereby alerting the clinician to the diagnosis of IBD before the onset of gastrointestinal symptoms. Nine children are reported who had no gastrointestinal symptoms suggestive of IBD but presented with mucocutaneous findings of IBD and were subsequently diagnosed with Crohn's disease or ulcerative colitis based on characteristic features on gastrointestinal endoscopy and/or biopsies. The majority of the patients had oral and perianal lesions. We believe that IBD is a common etiology for persistent oral lesions in the pediatric population. In addition to a good history, children with unexplained oral mucous membrane lesions should have an examination of the rectal and genital mucosa as well as tests for complete blood count, iron levels, sedimentation rate, albumin, and occult blood in the stool with endoscopy and biopsies to rule out IBD if indicated.

Author List

Galbraith SS, Drolet BA, Kugathasan S, Paller AS, Esterly NB

MESH terms used to index this publication - Major topics in bold

Child
Crohn Disease
Gingival Diseases
Humans
Hyperplasia
Lip Diseases
Mouth Diseases
Mouth Mucosa
Oral Ulcer
Pyoderma Gangrenosum