Nephroblastoma (Wilms tumor): tubule density and prognosis. Med Pediatr Oncol 1978;5(1):127-35
Date
01/01/1978Pubmed ID
218087DOI
10.1002/mpo.2950050119Scopus ID
2-s2.0-0018196664 (requires institutional sign-in at Scopus site) 4 CitationsAbstract
Relative differences in tubules density of the primary tumors have been suggested to be prognostically useful in nephroblastoma (Wilms tumor). Forty cases from our institution were retrospectively graded according to tubule density. There were significant differences in disease-free survivals between histologic grades. When compared to other clinical and pathologic staging criteria, tubule density was not more useful prognostically than the staging systems tested. However, when used in conjunction with clinical or pathologic stage, tumor grade improved prognostic sensitivity. Regardless of grade or stage, patients less than 24-months-old at diagnosis had better disease-free survival.
Author List
Chambers CH, Camitta BM, Garg U, Tang TT, McCreadie SRMESH terms used to index this publication - Major topics in bold
Age FactorsCell Differentiation
Child, Preschool
Humans
Infant
Kidney Tubules
Neoplasm Invasiveness
Neoplasm Staging
Prognosis
Retrospective Studies
Wilms Tumor
