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Nephroblastoma (Wilms tumor): tubule density and prognosis. Med Pediatr Oncol 1978;5(1):127-35 PMID: 218087

Pubmed ID

218087

Abstract

Relative differences in tubules density of the primary tumors have been suggested to be prognostically useful in nephroblastoma (Wilms tumor). Forty cases from our institution were retrospectively graded according to tubule density. There were significant differences in disease-free survivals between histologic grades. When compared to other clinical and pathologic staging criteria, tubule density was not more useful prognostically than the staging systems tested. However, when used in conjunction with clinical or pathologic stage, tumor grade improved prognostic sensitivity. Regardless of grade or stage, patients less than 24-months-old at diagnosis had better disease-free survival.

Author List

Chambers CH, Camitta BM, Garg U, Tang TT, McCreadie SR

Author

Bruce M. Camitta MD Clinical Professor in the Medicine department at Medical College of Wisconsin




Scopus

2-s2.0-0018196664   4 Citations

MESH terms used to index this publication - Major topics in bold

Age Factors
Cell Differentiation
Child, Preschool
Humans
Infant
Kidney Tubules
Neoplasm Invasiveness
Neoplasm Staging
Prognosis
Retrospective Studies
Wilms Tumor
jenkins-FCD Prod-353 9ccd8489072cb19f5b9f808bb23ed672c582f41e