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Spontaneous Intracranial Hypotension With Site of Leak Detected Only After 111In-DTPA Cisternogram. Clin Nucl Med 2017 Apr;42(4):e221-e223 PMID: 28079571


A 54-year-old man with a 3-week history of orthostatic headache and acute on chronic subdural hematoma presented with imaging findings suggestive of spontaneous intracranial hypotension. Three myelograms were negative for leak, and nontargeted epidural blood patches did not result in symptom relief. A cerebrospinal fluid leak study using In-DTPA with SPECT/CT demonstrated a focal area of asymmetric activity at the left C2 nerve root. A left C2 root tie-off, targeted epidural blood patch, and Dura seal glue resulted in resolution of patient symptomatology highlighting the importance of fused SPECT/CT images in detection of an occult cerebral spinal fluid leak.

Author List

Parsian S, Matesan MC, Kumbhar SS, Lewis DH


Sachin Kumbhar MD Assistant Professor in the Radiology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Indium Radioisotopes
Intracranial Hypotension
Middle Aged
Pentetic Acid

View this publication's entry at the Pubmed website PMID: 28079571
jenkins-FCD Prod-130 96200611f8481f0aa4f84230b11dd74d063847a3