Faculty Collaboration Database

Genomic Pathology and Cancer Biomarkers: Prostate Cancer. Crit Rev Oncog 2017;22(5-6):515-525

Date

01/01/2017

Pubmed ID

29604929

DOI

10.1615/CritRevOncog.2017020539

Scopus ID

2-s2.0-85059244722

Abstract

Our understanding of genomic pathology and biomarkers for prostate cancer is continually growing. Some promising and useful tissue markers are GSTP1, HOXD3, cell cycle proteins, chromatin remodeling proteins, androgen receptor, Stat5a/b, ERG, and PTEN. Serum and urine markers are mostly either prostate-specific antigen or newer tests using one or more other kallikreins or sarcosine. The data and evidence for all of these markers and the commercial tests using them are reviewed here.

Author List

Iczkowski KA

Author

Kenneth A. Iczkowski MD Professor in the Pathology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Biomarkers, Tumor
Genomics
Glutathione S-Transferase pi
Homeodomain Proteins
Humans
Kallikreins
Male
Prostate-Specific Antigen
Prostatic Neoplasms