Medical College of Wisconsin
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Hypopigmented onychocytic matricoma as a clinical mimic of onychomatricoma: clinical, intraoperative and histopathologic correlations. J Cutan Pathol 2013 Jun;40(6):591-4 PMID: 23521538

Pubmed ID

23521538

DOI

10.1111/cup.12122

Abstract

Onychocytic matricoma is a newly described matrical tumor of the nail unit that clinically presents with localized thickening of the nail plate and melanonychia and represents a benign acanthoma of onychocytes. Onychocytic matricoma can be classified according to its histopathologic type (acanthotic, papillomatous or keratogenous with retarded maturation) and pigmentation (pigmented, melanocytic or non-pigmented). However, there are no published reports of non-pigmented onychocytic matricoma. We report a case of hypopigmented onychocytic matricoma that presented with a thickened nail plate, xanthonychia and histopathologic features of acanthosis, prekeratogenous zone and keratogenous zone cells forming pseudosquamous eddies, and minimal pigmentation with Fontana staining. We also provide detailed clinical, intraoperative and histopathologic correlations of this rare tumor. Both clinicians and dermatopathologists should be aware that onychocytic matricoma can present with xanthonychia, thickening of the nail plate and mimic an onychomatricoma.

Author List

Spaccarelli N, Wanat KA, Miller CJ, Rubin AI

Author

Karolyn A. Wanat MD Associate Professor in the Dermatology department at Medical College of Wisconsin




Scopus

2-s2.0-84877574888   11 Citations

MESH terms used to index this publication - Major topics in bold

Aged
Humans
Male
Nail Diseases
Skin Neoplasms
Skin Pigmentation
jenkins-FCD Prod-310 bff9d975ec7f2d302586822146c2801dd4449aad