Medical College of Wisconsin
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Hypopigmented onychocytic matricoma as a clinical mimic of onychomatricoma: clinical, intraoperative and histopathologic correlations. J Cutan Pathol 2013 Jun;40(6):591-4 PMID: 23521538

Pubmed ID





Onychocytic matricoma is a newly described matrical tumor of the nail unit that clinically presents with localized thickening of the nail plate and melanonychia and represents a benign acanthoma of onychocytes. Onychocytic matricoma can be classified according to its histopathologic type (acanthotic, papillomatous or keratogenous with retarded maturation) and pigmentation (pigmented, melanocytic or non-pigmented). However, there are no published reports of non-pigmented onychocytic matricoma. We report a case of hypopigmented onychocytic matricoma that presented with a thickened nail plate, xanthonychia and histopathologic features of acanthosis, prekeratogenous zone and keratogenous zone cells forming pseudosquamous eddies, and minimal pigmentation with Fontana staining. We also provide detailed clinical, intraoperative and histopathologic correlations of this rare tumor. Both clinicians and dermatopathologists should be aware that onychocytic matricoma can present with xanthonychia, thickening of the nail plate and mimic an onychomatricoma.

Author List

Spaccarelli N, Wanat KA, Miller CJ, Rubin AI


Karolyn A. Wanat MD Associate Professor in the Dermatology department at Medical College of Wisconsin


2-s2.0-84877574888   12 Citations

MESH terms used to index this publication - Major topics in bold

Nail Diseases
Skin Neoplasms
Skin Pigmentation
jenkins-FCD Prod-332 f92a19b0ec5e8e1eff783fac390ec127e367c2b5