Mesh term Tumor Necrosis Factor-alpha
Browse to parent terms:Blood Proteins
Glycoproteins
Monokines
Tumor Necrosis Factors
Description
Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.Search for this term in our Faculty Database
View this term at the NCBI website
