Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Mesh term von Willebrand Factor

Browse to parent terms:
Blood Coagulation Factors

Description

A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor.



Search for this term in our Faculty Database



View this term at the NCBI website
jenkins-FCD Prod-468 69a93cef3257f26b866d455c1d2b2d0f28382f14