Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Mesh term PDZ Domains

Browse to parent terms:
Protein Interaction Domains and Motifs

Description

Protein interaction domains of about 70-90 amino acid residues, named after a common structure found in PSD-95, Discs Large, and Zona Occludens 1 proteins. PDZ domains are involved in the recruitment and interaction of proteins, and aid the formation of protein scaffolds and signaling networks. This is achieved by sequence-specific binding between a PDZ domain in one protein and a PDZ motif in another protein.



Search for this term in our Faculty Database



View this term at the NCBI website