Medical College of Wisconsin
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Renal adaptive changes and sodium handling in the fetal-to-newborn transition. Semin Fetal Neonatal Med 2017 04;22(2):76-82

Date

11/25/2016

Pubmed ID

27881286

DOI

10.1016/j.siny.2016.11.002

Scopus ID

2-s2.0-85006868071   4 Citations

Abstract

Appropriate fluid and electrolyte management is critical for optimal care of very low birth weight or sick infants. Delivery of such care requires an understanding of developmental changes in renal water and salt handling that occur with advancing gestational age as well as postnatal age. This review focuses on the principles of sodium homeostasis during fetal and postnatal life. The physiology of renal tubular transport mechanisms, as well as neurohumoral factors impacting renal tubular transport are highlighted. Clinical implications and guidelines to the provision of sodium to this vulnerable population are also discussed.

Author List

Segar JL

Author

Jeffrey L. Segar MD Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adaptation, Physiological
Humans
Infant, Newborn
Ion Transport
Kidney
Sodium
Water-Electrolyte Balance
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