Renal adaptive changes and sodium handling in the fetal-to-newborn transition. Semin Fetal Neonatal Med 2017 Apr;22(2):76-82
Date
11/25/2016Pubmed ID
27881286DOI
10.1016/j.siny.2016.11.002Scopus ID
2-s2.0-85006868071 (requires institutional sign-in at Scopus site) 24 CitationsAbstract
Appropriate fluid and electrolyte management is critical for optimal care of very low birth weight or sick infants. Delivery of such care requires an understanding of developmental changes in renal water and salt handling that occur with advancing gestational age as well as postnatal age. This review focuses on the principles of sodium homeostasis during fetal and postnatal life. The physiology of renal tubular transport mechanisms, as well as neurohumoral factors impacting renal tubular transport are highlighted. Clinical implications and guidelines to the provision of sodium to this vulnerable population are also discussed.
Author List
Segar JLAuthor
Jeffrey L. Segar MD Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Adaptation, PhysiologicalHumans
Infant, Newborn
Ion Transport
Kidney
Sodium
Water-Electrolyte Balance
