Faculty Collaboration Database

The effect of inhaled nitric oxide therapy on bleeding time and platelet aggregation in neonates. J Pediatr 1998 Apr;132(4):731-4

Date

05/15/1998

Pubmed ID

9580780

DOI

10.1016/s0022-3476(98)70370-1

Scopus ID

2-s2.0-0031925241   81 Citations

Abstract

The effect of inhaled nitric oxide (iNO) on bleeding time and platelet aggregation was studied in nine newborn infants with resolving pulmonary hypertension. Infants treated with iNO at 40 ppm for 30 minutes had bleeding times that were nearly twofold longer than those obtained 24 hours after iNO was discontinued. iNO had no effect on in vitro platelet aggregation studies.

Author List

George TN, Johnson KJ, Bates JN, Segar JL

Author

Jeffrey L. Segar MD Professor in the Pediatrics department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Administration, Inhalation
Bleeding Time
Humans
Infant, Newborn
Nitric Oxide
Persistent Fetal Circulation Syndrome
Platelet Aggregation