Faculty Collaboration Database

Mechanisms regulating renal sodium excretion during development. Pediatr Nephrol 1992 Mar;6(2):205-13

Date

03/01/1992

Pubmed ID

1533309

DOI

10.1007/BF00866320

Scopus ID

2-s2.0-0026532935   39 Citations

Abstract

The present review focuses on the ontogeny of mechanisms involved in renal sodium excretion during renal maturation. The effect of birth on renal excretion of sodium and the role played by the different tubular segments in the regulation of sodium excretion during maturation are discussed. The influence of circulating catecholamines and renal sympathetic innervation in regulating sodium excretion during renal development is reviewed. The effects of aldosterone, atrial natriuretic factor, and prostaglandins on sodium regulation during renal maturation are discussed. Special emphasis is given to the potential role of glucocorticoids in modulating sodium excretion early in life.

Author List

Robillard JE, Smith FG, Segar JL, Guillery EN, Jose PA

Author

Jeffrey L. Segar MD Professor in the Pediatrics department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Aldosterone
Animals
Atrial Natriuretic Factor
Catecholamines
Glucocorticoids
Homeostasis
Humans
Kidney
Prostaglandins
Renin-Angiotensin System
Sodium
Sympathetic Nervous System
Water-Electrolyte Balance