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Rapid rate on quasi-speech tasks in the semantic variant of primary progressive aphasia: A non-motor phenomenon? J Acoust Soc Am 2018 Dec;144(6):3364

Date

01/03/2019

Pubmed ID

30599666

Pubmed Central ID

PMC6296908

DOI

10.1121/1.5082210

Scopus ID

2-s2.0-85058811588 (requires institutional sign-in at Scopus site)   4 Citations

Abstract

This study examined the rate of producing alternating motion rates, sequential motion rates (SMRs), and repeated words in 27 individuals with the semantic variant of Primary Progressive Aphasia (svPPA). Only the rate of producing SMRs was significantly elevated in svPPA compared to controls. This may be associated with concomitant neuropsychiatric symptoms in svPPA, as correlation analysis showed a relationship between increased SMR rate and the Neuropsychiatric Inventory Questionnaire, which documented anxiety and disinhibition. Future studies will assess these findings in a larger cohort and work to better understand if this phenomenon is a manifestation of behavioral and/or motor changes.

Author List

Utianski RL, Botha H, Duffy JR, Clark HM, Martin PR, Butts AM, Machulda MM, Whitwell JL, Josephs KA

Author

Alissa Butts PhD Associate Professor in the Neurology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Aged
Aphasia, Primary Progressive
Female
Humans
Male
Middle Aged
Semantics
Speech