Rapid rate on quasi-speech tasks in the semantic variant of primary progressive aphasia: A non-motor phenomenon? J Acoust Soc Am 2018 Dec;144(6):3364
Date
01/03/2019Pubmed ID
30599666Pubmed Central ID
PMC6296908DOI
10.1121/1.5082210Scopus ID
2-s2.0-85058811588 (requires institutional sign-in at Scopus site) 4 CitationsAbstract
This study examined the rate of producing alternating motion rates, sequential motion rates (SMRs), and repeated words in 27 individuals with the semantic variant of Primary Progressive Aphasia (svPPA). Only the rate of producing SMRs was significantly elevated in svPPA compared to controls. This may be associated with concomitant neuropsychiatric symptoms in svPPA, as correlation analysis showed a relationship between increased SMR rate and the Neuropsychiatric Inventory Questionnaire, which documented anxiety and disinhibition. Future studies will assess these findings in a larger cohort and work to better understand if this phenomenon is a manifestation of behavioral and/or motor changes.
Author List
Utianski RL, Botha H, Duffy JR, Clark HM, Martin PR, Butts AM, Machulda MM, Whitwell JL, Josephs KAAuthor
Alissa Butts PhD Associate Professor in the Neurology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AgedAphasia, Primary Progressive
Female
Humans
Male
Middle Aged
Semantics
Speech