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Mineralocorticoid-receptor signalling in vascular smooth muscle. Nephrol Dial Transplant 2013 Jun;28(6):1360-2

Date

02/27/2013

Pubmed ID

23439586

Pubmed Central ID

PMC4007112

DOI

10.1093/ndt/gfs562

Scopus ID

2-s2.0-84879876047 (requires institutional sign-in at Scopus site)   2 Citations

Abstract

Human data suggest that eplerenone and spironolactone lowers blood pressure by mechanisms independent of the distal tubule. Now, a novel inducible conditional knockout model of the mineralocorticoid receptor (MR) in vascular smooth muscle cells (VSMCs) brings out understanding further.

Author List

Wu J, Luft FC



MESH terms used to index this publication - Major topics in bold

Animals
Blood Pressure
Humans
Mineralocorticoid Receptor Antagonists
Muscle, Smooth, Vascular
Receptors, Mineralocorticoid