Distribution of Lyb-4.1 and other membrane antigens on murine lymphoid tumors. J Natl Cancer Inst 1979 Aug;63(2):375-8
Date
08/01/1979Pubmed ID
313471DOI
10.1093/jnci/63.2.375Scopus ID
2-s2.0-0018673703 (requires institutional sign-in at Scopus site) 2 CitationsAbstract
The distribution of membrane antigens on 6 DBA/2-derived tumors (L1210, L5178Y, P815, ABLS 11, ABLS 12, and ABLS 13) was studied by direct cytotoxicity and quantitative absorption assays. Lyb-4.1 antigen was found solely on the L1210 tumor. Iad antigens were absent from all tumors, and H-2Kd and H-2Dd antigens were present on all tumors. Immunoglobulin was adsorbed to the ascites tumors and lost after 3 days or more in tissue culture. These studies were performed to characterize the distribution of DBA/2 membrane antigens on DBA/2-derived tumors as a base line for functional and chemical studies with these tumors and with their solubilized proteins.
Author List
Howe RC, Nelson RS, Rogan KM, Ahmed A, Aiken JJ, Dorf ME, Scherer JC, Sell KW, Humphreys REAuthor
John J. Aiken MD Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsAntigens, Neoplasm
Antigens, Surface
B-Lymphocytes
H-2 Antigens
Isoantigens
Leukemia L1210
Leukemia, Experimental
Lymphoma
Membrane Proteins
Mice
Mice, Inbred Strains
Neoplasm Proteins
