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Severe lead toxicity attributed to bullet fragments retained in soft tissue. BMJ Case Rep 2017 Mar 08;2017

Date

03/10/2017

Pubmed ID

28275014

Pubmed Central ID

PMC5353372

DOI

10.1136/bcr-2016-217351

Scopus ID

2-s2.0-85015243781 (requires institutional sign-in at Scopus site)   9 Citations

Abstract

A man aged 30 years presented to an emergency department with a 1 month history of severe abdominal pain, jaundice, constipation, lower extremity weakness and weight loss. A peripheral blood smear was performed that showed basophilic stippling of erythrocytes prompting a blood lead level (BLL) evaluation. The patient had a BLL of >200 µg/dL. Retained bullet fragments were identified in the left lower extremity from a previous gunshot wound 10 years prior. Lead from the excised bullet fragment was consistent with the patient's blood lead by isotope ratio analysis. This case is a rare example of a severely elevated BLL attributed to bullet fragments in soft tissue. Bullets retained in soft tissue are not often considered a risk factor for a markedly elevated BLL because they become encapsulated within the tissue over time.

Author List

Weiss D, Lee D, Feldman R, Smith KE

Author

Ryan J. Feldman PharmD Adjunct Assistant Professor in the School of Pharmacy Administration department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adult
Disease Management
Foreign Bodies
Humans
Lead Poisoning
Male
Wounds, Gunshot